A clickable psoralen to directly quantify DNA interstrand crosslinking and repair

von Evison, Benjamin J., Actis, Marcelo L., Fujii, Naoaki
Veröffentlicht in Bioorg Med Chem (2016)

A novel assay revealed that ribonucleotide reductase is functionally important for interstrand DNA crosslink repair

von Fujii, Naoaki, Evison, Benjamin J., Actis, Marcelo L., Inoue, Akira
Veröffentlicht in Bioorg Med Chem (2015)

A site-selective, irreversible inhibitor of the DNA replication auxiliary factor proliferating cell nuclear antigen (PCNA)

von Evison, Benjamin J., Actis, Marcelo L., Wu, Zhexiang, Shao, Youming, Heath, Richard J., Yang, Lei, Fujii, Naoaki
Veröffentlicht in Bioorg Med Chem (2014)

Small-molecules that bind to the ubiquitin-binding motif of REV1 inhibit REV1 interaction with K164-monoubiquitinated PCNA and suppress DNA damage tolerance

von Vanarotti, Murugendra, Evison, Benjamin J., Actis, Marcelo L., Inoue, Akira, McDonald, Ezelle T., Shao, Youming, Heath, Richard J., Fujii, Naoaki
Veröffentlicht in Bioorg Med Chem (2018)

A Small Molecule Inhibitor of Monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) Inhibits Repair of Interstrand DNA Cross-link, Enhances DNA Double Strand Break, and Sensi...

von Inoue, Akira, Kikuchi, Sotaro, Hishiki, Asami, Shao, Youming, Heath, Richard, Evison, Benjamin J., Actis, Marcelo, Canman, Christine E., Hashimoto, Hiroshi, Fujii, Naoaki
Veröffentlicht 2014

Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction

von Actis, Marcelo L., Ambaye, Nigus D., Evison, Benjamin J., Shao, Youming, Vanarotti, Murugendra, Inoue, Akira, McDonald, Ezelle T., Kikuchi, Sotaro, Heath, Richard, Hara, Kodai, Hashimoto, Hiroshi, Fujii, Naoaki
Veröffentlicht in Bioorg Med Chem (2016)

Capturing the direct binding of CFTR correctors to CFTR using click chemistry

von Sinha, Chandrima, Zhang, Weiqiang, Moon, Chang Suk, Actis, Marcelo, Yarlagadda, Sunitha, Arora, Kavisha, Woodroofe, Koryse, Clancy, John P., Lin, Songbai, Ziady, Assem G., Frizzell, Raymond, Fujii, Naoaki, Naren, Anjaparavanda P.
Veröffentlicht in Chembiochem (2015)

Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3

von Kamadurai, Hari B, Qiu, Yu, Deng, Alan, Harrison, Joseph S, MacDonald, Chris, Actis, Marcelo, Rodrigues, Patrick, Miller, Darcie J, Souphron, Judith, Lewis, Steven M, Kurinov, Igor, Fujii, Naoaki, Hammel, Michal, Piper, Robert, Kuhlman, Brian, Schulman, Brenda A
Veröffentlicht 2013

RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex

von Brown, Nicholas G., VanderLinden, Ryan, Watson, Edmond R., Qiao, Renping, Grace, Christy R. R., Yamaguchi, Masaya, Weissmann, Florian, Frye, Jeremiah J., Dube, Prakash, Ei Cho, Shein, Actis, Marcelo L., Rodrigues, Patrick, Fujii, Naoaki, Peters, Jan-Michael, Stark, Holger, Schulman, Brenda A.
Veröffentlicht in Proc Natl Acad Sci U S A (2015)

NALP3 inflammasome up-regulation and CASP1 cleavage of the glucocorticoid receptor causes glucocorticoid resistance in leukemia cells

von Paugh, Steven W., Bonten, Erik J., Savic, Daniel, Ramsey, Laura B., Thierfelder, William E., Gurung, Prajwal, Malireddi, R. K. Subbarao, Actis, Marcelo, Mayasundari, Anand, Min, Jaeki, Coss, David R., Laudermilk, Lucas T., Panetta, John C., McCorkle, J. Robert, Fan, Yiping, Crews, Kristine R., Stocco, Gabriele, Wilkinson, Mark R., Ferreira, Antonio M., Cheng, Cheng, Yang, Wenjian, Karol, Seth E., Fernandez, Christian A., Diouf, Barthelemy, Smith, Colton, Hicks, J. Kevin, Zanut, Alessandra, Giordanengo, Audrey, Crona, Daniel, Bianchi, Joy J., Holmfeldt, Linda, Mullighan, Charles G., den Boer, Monique L., Pieters, Rob, Jeha, Sima, Dunwell, Thomas L., Latif, Farida, Bhojwani, Deepa, Carroll, William L., Pui, Ching-Hon, Myers, Richard M., Guy, R. Kiplin, Kanneganti, Thirumala-Devi, Relling, Mary V., Evans, William E.
Veröffentlicht in Nat Genet (2015)