Skeletal Muscle Modulates Huntington’s Disease Pathogenesis in Mice: Role of Physical Exercise

par Corrochano, Silvia, Blanco, Gonzalo, Acevedo-Arozena, Abraham
Publié dans J Exp Neurosci (2018)

Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis

par De Giorgio, Francesca, Maduro, Cheryl, Fisher, Elizabeth M. C., Acevedo-Arozena, Abraham
Publié dans Dis Model Mech (2019)

Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease

par Rose, Claudia, Menzies, Fiona M., Renna, Maurizio, Acevedo-Arozena, Abraham, Corrochano, Silvia, Sadiq, Oana, Brown, Steve D., Rubinsztein, David C.
Publié 2010

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease

par Tateossian, Hilda, Morse, Susan, Parker, Andrew, Mburu, Philomena, Warr, Nick, Acevedo-Arozena, Abraham, Cheeseman, Michael, Wells, Sara, Brown, Steve D.M.
Publié 2013

α-Synuclein levels modulate Huntington's disease in mice

par Corrochano, Silvia, Renna, Maurizio, Carter, Sarah, Chrobot, Nichola, Kent, Rose, Stewart, Michelle, Cooper, Jason, Brown, Steve D.M., Rubinsztein, David C., Acevedo-Arozena, Abraham
Publié 2012

α-Synuclein levels modulate Huntington's disease in mice

par Corrochano, Silvia, Renna, Maurizio, Carter, Sarah, Chrobot, Nichola, Kent, Rose, Stewart, Michelle, Cooper, Jason, Brown, Steve D.M., Rubinsztein, David C., Acevedo-Arozena, Abraham
Publié 2012

Reducing Igf-1r Levels Leads To Paradoxical and Sexually Dimorphic Effects in HD Mice

par Corrochano, Silvia, Renna, Maurizio, Osborne, Georgina, Carter, Sarah, Stewart, Michelle, May, Joel, Bates, Gillian P., Brown, Steve D. M., Rubinsztein, David C., Acevedo-Arozena, Abraham
Publié 2014

A Nonsense Mutation in Mouse Tardbp Affects TDP43 Alternative Splicing Activity and Causes Limb-Clasping and Body Tone Defects

par Ricketts, Thomas, McGoldrick, Philip, Fratta, Pietro, de Oliveira, Hugo M., Kent, Rosie, Phatak, Vinaya, Brandner, Sebastian, Blanco, Gonzalo, Greensmith, Linda, Acevedo-Arozena, Abraham, Fisher, Elizabeth M. C.
Publié 2014

Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy()

par Cortese, Andrea, Plagnol, Vincent, Brady, Stefen, Simone, Roberto, Lashley, Tammaryn, Acevedo-Arozena, Abraham, de Silva, Rohan, Greensmith, Linda, Holton, Janice, Hanna, Michael G., Fisher, Elizabeth M.C., Fratta, Pietro
Publié 2014

A comprehensive assessment of the SOD1(G93A) low-copy transgenic mouse, which models human amyotrophic lateral sclerosis

par Acevedo-Arozena, Abraham, Kalmar, Bernadett, Essa, Shafa, Ricketts, Thomas, Joyce, Peter, Kent, Rosie, Rowe, Claire, Parker, Andy, Gray, Anna, Hafezparast, Majid, Thorpe, Julian R., Greensmith, Linda, Fisher, Elizabeth M. C.
Publié 2011

Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis System

par Bains, Rasneer S., Cater, Heather L., Sillito, Rowland R., Chartsias, Agisilaos, Sneddon, Duncan, Concas, Danilo, Keskivali-Bond, Piia, Lukins, Timothy C., Wells, Sara, Acevedo Arozena, Abraham, Nolan, Patrick M., Armstrong, J. Douglas
Publié dans Front Behav Neurosci (2016)

Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities

par Stewart, Michelle, Lau, Petrina, Banks, Gareth, Bains, Rasneer Sonia, Castroflorio, Enrico, Oliver, Peter L., Dixon, Christine L., Kruer, Michael C., Kullmann, Dimitri M., Acevedo-Arozena, Abraham, Wells, Sara E., Corrochano, Silvia, Nolan, Patrick M.
Publié dans Dis Model Mech (2019)

α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

par Winslow, Ashley R., Chen, Chien-Wen, Corrochano, Silvia, Acevedo-Arozena, Abraham, Gordon, David E., Peden, Andrew A., Lichtenberg, Maike, Menzies, Fiona M., Ravikumar, Brinda, Imarisio, Sara, Brown, Steve, O’Kane, Cahir J., Rubinsztein, David C.
Publié 2010

IGF-1 receptor antagonism inhibits autophagy

par Renna, Maurizio, Bento, Carla F., Fleming, Angeleen, Menzies, Fiona M., Siddiqi, Farah H., Ravikumar, Brinda, Puri, Claudia, Garcia-Arencibia, Moises, Sadiq, Oana, Corrochano, Silvia, Carter, Sarah, Brown, Steve D.M., Acevedo-Arozena, Abraham, Rubinsztein, David C.
Publié 2013

A genetic modifier suggests that endurance exercise exacerbates Huntington's disease

par Corrochano, Silvia, Blanco, Gonzalo, Williams, Debbie, Wettstein, Jessica, Simon, Michelle, Kumar, Saumya, Moir, Lee, Agnew, Thomas, Stewart, Michelle, Landman, Allison, Kotiadis, Vassilios N, Duchen, Michael R, Wackerhage, Henning, Rubinsztein, David C, Brown, Steve D M, Acevedo-Arozena, Abraham
Publié dans Hum Mol Genet (2018)

Behavioral and Other Phenotypes in a Cytoplasmic Dynein Light Intermediate Chain 1 Mutant Mouse

par Banks, Gareth T., Haas, Matilda A., Line, Samantha, Shepherd, Hazel L., AlQatari, Mona, Stewart, Sammy, Rishal, Ida, Philpott, Amelia, Kalmar, Bernadett, Kuta, Anna, Groves, Michael, Parkinson, Nicholas, Acevedo-Arozena, Abraham, Brandner, Sebastian, Bannerman, David, Greensmith, Linda, Hafezparast, Majid, Koltzenburg, Martin, Deacon, Robert, Fainzilber, Mike, Fisher, Elizabeth M. C.
Publié 2011

Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in ‘FUSDelta14’ knockin mice

par Devoy, Anny, Kalmar, Bernadett, Stewart, Michelle, Park, Heesoon, Burke, Beverley, Noy, Suzanna J, Redhead, Yushi, Humphrey, Jack, Lo, Kitty, Jaeger, Julian, Mejia Maza, Alan, Sivakumar, Prasanth, Bertolin, Cinzia, Soraru, Gianni, Plagnol, Vincent, Greensmith, Linda, Acevedo Arozena, Abraham, Isaacs, Adrian M, Davies, Benjamin, Fratta, Pietro, Fisher, Elizabeth M C
Publié dans Brain (2017)

EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome

par Tan, Shengjiang, Kermasson, Laëtitia, Hoslin, Angela, Jaako, Pekka, Faille, Alexandre, Acevedo-Arozena, Abraham, Lengline, Etienne, Ranta, Dana, Poirée, Maryline, Fenneteau, Odile, Ducou le Pointe, Hubert, Fumagalli, Stefano, Beaupain, Blandine, Nitschké, Patrick, Bôle-Feysot, Christine, de Villartay, Jean-Pierre, Bellanné-Chantelot, Christine, Donadieu, Jean, Kannengiesser, Caroline, Warren, Alan J., Revy, Patrick
Publié dans Blood (2019)

A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

par Joyce, Peter I., Mcgoldrick, Philip, Saccon, Rachele A., Weber, William, Fratta, Pietro, West, Steven J., Zhu, Ning, Carter, Sarah, Phatak, Vinaya, Stewart, Michelle, Simon, Michelle, Kumar, Saumya, Heise, Ines, Bros-Facer, Virginie, Dick, James, Corrochano, Silvia, Stanford, Macdonnell J., Luong, Tu Vinh, Nolan, Patrick M., Meyer, Timothy, Brandner, Sebastian, Bennett, David L.H., Ozdinler, P. Hande, Greensmith, Linda, Fisher, Elizabeth M.C., Acevedo-Arozena, Abraham
Publié dans Hum Mol Genet (2015)

Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis

par Corrochano, Silvia, Männikkö, Roope, Joyce, Peter I., McGoldrick, Philip, Wettstein, Jessica, Lassi, Glenda, Raja Rayan, Dipa L., Blanco, Gonzalo, Quinn, Colin, Liavas, Andrianos, Lionikas, Arimantas, Amior, Neta, Dick, James, Healy, Estelle G., Stewart, Michelle, Carter, Sarah, Hutchinson, Marie, Bentley, Liz, Fratta, Pietro, Cortese, Andrea, Cox, Roger, Brown, Steve D. M., Tucci, Valter, Wackerhage, Henning, Amato, Anthony A., Greensmith, Linda, Koltzenburg, Martin, Hanna, Michael G., Acevedo-Arozena, Abraham
Publié dans Brain (2014)