A carregar...
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by a polyglutamine expansion in huntingtin. There are no treatments that are known to slow the neurodegeneration caused by this mutation. Mutant huntingtin causes disease via a toxic gain-of-function mechanism a...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865373/ https://ncbi.nlm.nih.gov/pubmed/20190273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq093 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|