Mouse Models of Age-related Mitochondrial Neurosensory Hearing Loss

Por Han, Chul, Someya, Shinichi
Publicado em 2012

Maintaining good hearing: Calorie restriction, Sirt3, and glutathione

Por Han, Chul, Someya, Shinichi
Publicado em 2013

Mitochondrial oxidative damage and apoptosis in age-related hearing loss

Por Someya, Shinichi, Prolla, Tomas A.
Publicado em 2010

Effects of Caloric Restriction on Age-Related Hearing Loss in Rodents and Rhesus Monkeys

Por Someya, Shinichi, Tanokura, Masaru, Weindruch, Richard, Prolla, Tomas A., Yamasoba, Tatsuya
Publicado em 2010

OTOTOXIC EFFECTS OF CARBOPLATIN IN ORGANOTYPIC CULTURES IN CHINCHILLAS AND RATS

Por Dalian, Ding, Haiyan, Jiang, Yong, Fu, Salvi, Richard, Someya, Shinichi, Tanokura, Masaru
Publicado no J Otol (2012)

Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics

Por Xu, Yuqun, Liu, Lingwen, Nakamura, Akira, Someya, Shinichi, Miyakawa, Takuya, Tanokura, Masaru
Publicado no Sci Rep (2017)

Current concepts in age-related hearing loss: Epidemiology and mechanistic pathways

Por Yamasoba, Tatsuya, Lin, Frank R., Someya, Shinichi, Kashio, Akinori, Sakamoto, Takashi, Kondo, Kenji
Publicado em 2013

Ototoxic Model of Oxaliplatin and Protection from Nicotinamide Adenine Dinucleotide

Por Dalian, Ding, Haiyan, Jiang, Yong, Fu, Yongqi, Li, Salvi, Richard, Someya, Shinichi, Tanokura, Masaru
Publicado no J Otol (2013)

Influence of Viral Vector–Mediated Delivery of Superoxide Dismutase and Catalase to the Hippocampus on Spatial Learning and Memory During Aging

Por Lee, Wei-Hua, Kumar, Ashok, Rani, Asha, Herrera, Jose, Xu, Jinze, Someya, Shinichi, Foster, Thomas C.
Publicado em 2012

GLAST Deficiency in Mice Exacerbates Gap Detection Deficits in a Model of Salicylate-Induced Tinnitus

Por Yu, Hong, Vikhe Patil, Kim, Han, Chul, Fabella, Brian, Canlon, Barbara, Someya, Shinichi, Cederroth, Christopher R.
Publicado no Front Behav Neurosci (2016)

The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase γ

Por Someya, Shinichi, Yamasoba, Tatsuya, Kujoth, Gregory C., Pugh, Thomas D., Weindruch, Richard, Tanokura, Masaru, Prolla, Tomas A.
Publicado em 2007

Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice

Por Someya, Shinichi, Kujoth, Gregory C., Kim, Mi-Jung, Hacker, Timothy A., Vermulst, Marc, Weindruch, Richard, Prolla, Tomas A.
Publicado no PLoS One (2017)

Health Effects of Long-Term Rapamycin Treatment: The Impact on Mouse Health of Enteric Rapamycin Treatment from Four Months of Age throughout Life

Por Fischer, Kathleen E., Gelfond, Jonathan A. L., Soto, Vanessa Y., Han, Chul, Someya, Shinichi, Richardson, Arlan, Austad, Steven N.
Publicado no PLoS One (2015)

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-related Hearing Loss under Caloric Restriction

Por Someya, Shinichi, Yu, Wei, Hallows, William C., Xu, Jinze, Vann, James M., Leeuwenburgh, Christiaan, Tanokura, Masaru, Denu, John M., Prolla, Tomas A.
Publicado em 2010

Sirt1 deficiency protects cochlear cells and delays the early onset of age-related hearing loss in C57BL/6 mice

Por Han, Chul, Linser, Paul, Park, Hyo-Jin, Kim, Mi-Jung, White, Karessa, Vann, James M., Ding, Dalian, Prolla, Tomas A., Someya, Shinichi
Publicado no Neurobiol Aging (2016)

G6pd Deficiency Does Not Affect the Cytosolic Glutathione or Thioredoxin Antioxidant Defense in Mouse Cochlea

Por White, Karessa, Kim, Mi-Jung, Ding, Dalian, Han, Chul, Park, Hyo-Jin, Meneses, Zaimary, Tanokura, Masaru, Linser, Paul, Salvi, Richard, Someya, Shinichi
Publicado no J Neurosci (2017)

LOSS OF SESTRIN 2 POTENTIATES THE EARLY ONSET OF AGE-RELATED SENSORY CELL DEGENERATION IN THE COCHLEA

Por ZHANG, CELIA, SUN, WEI, LI, JI, XIONG, BINBIN, FRYE, MITCHELL D., DING, DALIAN, SALVI, RICHARD, KIM, MI-JUNG, SOMEYA, SHINICHI, HU, BO HUA
Publicado no Neuroscience (2017)

Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis

Por Someya, Shinichi, Xu, Jinze, Kondo, Kenji, Ding, Dalian, Salvi, Richard J., Yamasoba, Tatsuya, Rabinovitch, Peter S., Weindruch, Richard, Leeuwenburgh, Christiaan, Tanokura, Masaru, Prolla, Tomas A.
Publicado em 2009

Intraoperative hemidiaphragm electrical stimulation reduces oxidative stress and upregulates autophagy in surgery patients undergoing mechanical ventilation: exploratory study

Por Mankowski, Robert T., Ahmed, Shakeel, Beaver, Thomas, Dirain, Marvin, Han, Chul, Hess, Phillip, Martin, Tomas, Smith, Barbara K., Someya, Shinichi, Leeuwenburgh, Christiaan, Martin, A. Daniel
Publicado no J Transl Med (2016)

A Conserved Transcriptional Signature of Delayed Aging and Reduced Disease Vulnerability Is Partially Mediated by SIRT3

Por Barger, Jamie L., Anderson, Rozalyn M., Newton, Michael A., da Silva, Cristina, Vann, James A., Pugh, Thomas D., Someya, Shinichi, Prolla, Tomas A., Weindruch, Richard
Publicado no PLoS One (2015)