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Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis

Age-related hearing loss (AHL), known as presbycusis, is a universal feature of mammalian aging and is the most common sensory disorder in the elderly population. The molecular mechanisms underlying AHL are unknown, and currently there is no treatment for the disorder. Here we report that C57BL/6J m...

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書誌詳細
主要な著者: Someya, Shinichi, Xu, Jinze, Kondo, Kenji, Ding, Dalian, Salvi, Richard J., Yamasoba, Tatsuya, Rabinovitch, Peter S., Weindruch, Richard, Leeuwenburgh, Christiaan, Tanokura, Masaru, Prolla, Tomas A.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780799/
https://ncbi.nlm.nih.gov/pubmed/19901338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908786106
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