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OTOTOXIC EFFECTS OF CARBOPLATIN IN ORGANOTYPIC CULTURES IN CHINCHILLAS AND RATS

Carboplatin, a second-generation platinum chemotherapeutic drug, is considerably less ototoxic than cisplatin. While common laboratory species such as mice, guinea pigs and rats are highly resistant to carboplatin ototoxicity, the chinchilla stands out as highly susceptible. Moreover, carboplatin ca...

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Detalhes bibliográficos
Publicado no:J Otol
Main Authors: Dalian, Ding, Haiyan, Jiang, Yong, Fu, Salvi, Richard, Someya, Shinichi, Tanokura, Masaru
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291553/
https://ncbi.nlm.nih.gov/pubmed/25593588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1672-2930(12)50023-1
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