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OTOTOXIC EFFECTS OF CARBOPLATIN IN ORGANOTYPIC CULTURES IN CHINCHILLAS AND RATS

Carboplatin, a second-generation platinum chemotherapeutic drug, is considerably less ototoxic than cisplatin. While common laboratory species such as mice, guinea pigs and rats are highly resistant to carboplatin ototoxicity, the chinchilla stands out as highly susceptible. Moreover, carboplatin ca...

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Bibliografske podrobnosti
izdano v:J Otol
Main Authors: Dalian, Ding, Haiyan, Jiang, Yong, Fu, Salvi, Richard, Someya, Shinichi, Tanokura, Masaru
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291553/
https://ncbi.nlm.nih.gov/pubmed/25593588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1672-2930(12)50023-1
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