Cathepsin D: Regulation in mammary gland remodeling, misregulation in breast cancer

Por Radisky, Evette S
Publicado em 2010

PRSS3/mesotrypsin in prostate cancer progression: implications for translational medicine

Por Radisky, Evette S
Publicado em 2013

Mirolysin structures open a window on gum disease

Por Radisky, Evette S.
Publicado no IUCrJ (2020)

Bad Tumors Made Worse: SPINK1

Por Mehner, Christine, Radisky, Evette S.
Publicado no Front Cell Dev Biol (2019)

A clogged gutter mechanism for protease inhibitors

Por Radisky, Evette S., Koshland, Daniel E.
Publicado em 2002

Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer

Por Radisky, Evette S., Radisky, Derek C.
Publicado em 2010

Matrix metalloproteinases as breast cancer drivers and therapeutic targets

Por Radisky, Evette S., Radisky, Derek C.
Publicado no Front Biosci (Landmark Ed) (2015)

Biochemical and structural insights into mesotrypsin: an unusual human trypsin

Por Salameh, Moh’d A, Radisky, Evette S
Publicado em 2013

Combinatorial engineering of N-TIMP2 variants that selectively inhibit MMP9 and MMP14 function in the cell

Por Arkadash, Valeria, Radisky, Evette S., Papo, Niv
Publicado no Oncotarget (2018)

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

Por Hockla, Alexandra, Radisky, Derek C., Radisky, Evette S.
Publicado em 2009

Zymogen Activation Confers Thermodynamic Stability on a Key Peptide Bond and Protects Human Cationic Trypsin from Degradation

Por Szabó, András, Radisky, Evette S., Sahin-Tóth, Miklós
Publicado em 2014

Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes

Por Batra, Jyotica, Soares, Alexei S., Mehner, Christine, Radisky, Evette S.
Publicado em 2013

Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer

Por Radisky, Evette S., Raeeszadeh‐Sarmazdeh, Maryam, Radisky, Derek C.
Publicado no J Cell Biochem (2017)

Quantitative Mapping of Binding Specificity Landscapes for Homologous Targets by using a High-Throughput Method

Por Aharon, Lidan, Aharoni, Shay-Lee, Radisky, Evette S., Papo, Niv
Publicado no Biochem J (2020)

Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors

Por Salameh, Moh'd A, Soares, Alexei S, Alloy, Alexandre, Radisky, Evette S
Publicado em 2012

Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates

Por Radisky, Evette S., Lee, Justin M., Lu, Chia-Jung Karen, Koshland, Daniel E.
Publicado em 2006

Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries

Por Naftaly, Si, Cohen, Itay, Shahar, Anat, Hockla, Alexandra, Radisky, Evette S., Papo, Niv
Publicado no Nat Commun (2018)

The P(2)′ residue is a key determinant of mesotrypsin specificity: Engineering a high affinity inhibitor with anticancer activity

Por Salameh, Moh’d A., Soares, Alexei S., Hockla, Alexandra, Radisky, Derek C., Radisky, Evette S.
Publicado em 2011

Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer

Por Mehner, Christine, Hockla, Alexandra, Miller, Erin, Ran, Sophia, Radisky, Derek C., Radisky, Evette S.
Publicado em 2014

Tyrosine Sulfation of Human Trypsin Steers S2’ Subsite Selectivity towards Basic Amino Acids

Por Szabó, András, Salameh, Moh’d A., Ludwig, Maren, Radisky, Evette S., Sahin-Tóth, Miklós
Publicado em 2014