Cathepsin K-Cre Causes Unexpected Germline Deletion of Genes in Mice

Por Winkeler, Crystal L., Kladney, Raleigh D., Maggi, Leonard B., Weber, Jason D.
Publicado em 2012

HYPOXIA-INDUCIBLE FACTOR-1α SUPPRESSES SQUAMOUS CARCINOGENIC PROGRESSION AND EPITHELIAL MESENCHYMAL TRANSITION

Por Scortegagna, Marzia, Martin, Rebecca J., Kladney, Raleigh D., Neumann, Robert G., Arbeit, Jeffrey M.
Publicado em 2009

Tuberous Sclerosis Complex 1: An Epithelial Tumor Suppressor Essential to Prevent Spontaneous Prostate Cancer in Aged Mice

Por Kladney, Raleigh D., Cardiff, Robert D., Kwiatkowski, David J., Chiang, Gary G., Weber, Jason D., Arbeit, Jeffrey M., Lu, Zhi Hong
Publicado em 2010

RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis

Por Saporita, Anthony J., Chang, Hsiang-Chun, Winkeler, Crystal L., Apicelli, Anthony J., Kladney, Raleigh D., Wang, Jianbo, Townsend, R. Reid, Michel, Loren S., Weber, Jason D.
Publicado em 2011

Loss of Trop2 Promotes Carcinogenesis and Features of Epithelial to Mesenchymal Transition in Squamous Cell Carcinoma

Por Wang, Jianbo, Zhang, Kaihua, Grabowska, Dorota, Li, Aimin, Dong, Yiyu, Day, Ryan, Humphrey, Peter, Lewis, James, Kladney, Raleigh D., Arbeit, Jeffrey M., Weber, Jason D., Chung, Christine H., Michel, Loren S.
Publicado em 2011

mTOR Activator Rheb Is Frequently Overexpressed In Human Carcinomas And Is Critical And Sufficient For Skin Epithelial Carcinogenesis

Por Lu, Zhi Hong, Shvartsman, Mark B., Lee, Andrew Y., Shao, Jenny M., Murray, Mollianne M., Kladney, Raleigh D., Fan, Dong, Krajewski, Stan, Chiang, Gary G., Mills, Gordon B., Arbeit, Jeffrey M.
Publicado em 2010

STAT3/PIAS3 levels serve as “early signature” genes in the development of high-grade serous carcinoma from the fallopian tube

Por Saini, Uksha, Suarez, Adrian A., Naidu, Shan, Wallbillich, John J., Bixel, Kristin, Wanner, Ross A., Bice, Jason, Kladney, Raleigh D., Lester, Jenny, Karlan, Beth Y., Goodfellow, Paul J., Cohn, David E., Selvendiran, Karuppaiyah
Publicado no Cancer Res (2018)

NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development

Por Ratnam, Nivedita M., Peterson, Jennifer M., Talbert, Erin E., Ladner, Katherine J., Rajasekera, Priyani V., Schmidt, Carl R., Dillhoff, Mary E., Swanson, Benjamin J., Haverick, Ericka, Kladney, Raleigh D., Williams, Terence M., Leone, Gustavo W., Wang, David J., Guttridge, Denis C.
Publicado no J Clin Invest (2017)

Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth

Por Hammer, Anisha M., Sizemore, Gina M., Shukla, Vasudha C., Avendano, Alex, Sizemore, Steven T., Chang, Jonathan J., Kladney, Raleigh D., Cuitiño, Maria C., Thies, Katie A., Verfurth, Quinn, Chakravarti, Arnab, Yee, Lisa D., Leone, Gustavo, Song, Jonathan W., Ghadiali, Samir N., Ostrowski, Michael C.
Publicado no Neoplasia (2017)

Golgi Protein GOLM1 Is a Tissue and Urine Biomarker of Prostate Cancer

Por Varambally, Sooryanarayana, Laxman, Bharathi, Mehra, Rohit, Cao, Qi, Dhanasekaran, Saravana M, Tomlins, Scott A, Granger, Jill, Vellaichamy, Adaikkalam, Sreekumar, Arun, Yu, Jianjun, Gu, Wenjuan, Shen, Ronglai, Ghosh, Debashis, Wright, Lorinda M, Kladney, Raleigh D, Kuefer, Rainer, Rubin, Mark A, Fimmel, Claus J, Chinnaiyan, Arul M
Publicado em 2008

Ets2 in Tumor Fibroblasts Promotes Angiogenesis in Breast Cancer

Por Wallace, Julie A., Li, Fu, Balakrishnan, Subhasree, Cantemir-Stone, Carmen Z., Pecot, Thierry, Martin, Chelsea, Kladney, Raleigh D., Sharma, Sudarshana M., Trimboli, Anthony J., Fernandez, Soledad A., Yu, Lianbo, Rosol, Thomas J., Stromberg, Paul C., Lesurf, Robert, Hallett, Michael, Park, Morag, Leone, Gustavo, Ostrowski, Michael C.
Publicado em 2013

Exosome-derived miR-25-3p and miR-92a-3p stimulate liposarcoma progression

Por Casadei, Lucia, Calore, Federica, Creighton, Chad J., Guescini, Michele, Batte, Kara, Iwenofu, O. Hans, Zewdu, Abeba, Braggio, Danielle A., Lynn Bill, Kate, Fadda, Paolo, Lovat, Francesca, Lopez, Gonzalo, Gasparini, Pierluigi, Chen, James L., Kladney, Raleigh D., Leone, Gustavo, Lev, Dina, Croce, Carlo M., Pollock, Raphael E.
Publicado no Cancer Res (2017)

Interleukin-18 drives ILC3 proliferation and promotes interleukin-22 production via NF-κB()

Por Victor, Aaron R., Nalin, Ansel P., Dong, Wenjuan, McClory, Susan, Wei, Min, Mao, Charlene, Kladney, Raleigh D., Youssef, Youssef, Chan, Wing Keung, Briercheck, Edward L., Hughes, Tiffany, Scoville, Steven D., Pitarresi, Jason R., Chen, Charlie, Manz, Sarah, Wu, Lai-Chu, Zhang, Jianying, Ostrowski, Michael C., Freud, Aharon G., Leone, Gustavo W., Caligiuri, Michael A., Yu, Jianhua
Publicado no J Immunol (2017)

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia()

Por Pitarresi, Jason R., Liu, Xin, Sharma, Sudarshana M., Cuitiño, Maria C., Kladney, Raleigh D., Mace, Thomas A., Donohue, Sydney, Nayak, Sunayana G., Qu, Chunjing, Lee, James, Woelke, Sarah A., Trela, Stefan, LaPak, Kyle, Yu, Lianbo, McElroy, Joseph, Rosol, Thomas J., Shakya, Reena, Ludwig, Thomas, Lesinski, Gregory B., Fernandez, Soledad A., Konieczny, Stephen F., Leone, Gustavo, Wu, Jinghai, Ostrowski, Michael C.
Publicado no Neoplasia (2016)

Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar–ductal metaplasia

Por Liu, Xin, Pitarresi, Jason R., Cuitiño, Maria C., Kladney, Raleigh D., Woelke, Sarah A., Sizemore, Gina M., Nayak, Sunayana G., Egriboz, Onur, Schweickert, Patrick G., Yu, Lianbo, Trela, Stefan, Schilling, Daniel J., Halloran, Shannon K., Li, Maokun, Dutta, Shourik, Fernandez, Soledad A., Rosol, Thomas J., Lesinski, Gregory B., Shakya, Reena, Ludwig, Thomas, Konieczny, Stephen F., Leone, Gustavo, Wu, Jinghai, Ostrowski, Michael C.
Publicado no Genes Dev (2016)

Stromal PTEN determines mammary epithelial response to radiotherapy

Por Sizemore, Gina M., Balakrishnan, Subhasree, Thies, Katie A., Hammer, Anisha M., Sizemore, Steven T., Trimboli, Anthony J., Cuitiño, Maria C., Steck, Sarah A., Tozbikian, Gary, Kladney, Raleigh D., Shinde, Neelam, Das, Manjusri, Park, Dongju, Majumder, Sarmila, Krishnan, Shiva, Yu, Lianbo, Fernandez, Soledad A., Chakravarti, Arnab, Shields, Peter G., White, Julia R., Yee, Lisa D., Rosol, Thomas J., Ludwig, Thomas, Park, Morag, Leone, Gustavo, Ostrowski, Michael C.
Publicado no Nat Commun (2018)

Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth

Por Pitarresi, Jason R, Liu, Xin, Avendano, Alex, Thies, Katie A, Sizemore, Gina M, Hammer, Anisha M, Hildreth, Blake E, Wang, David J, Steck, Sarah A, Donohue, Sydney, Cuitiño, Maria C, Kladney, Raleigh D, Mace, Thomas A, Chang, Jonathan J, Ennis, Christina S, Li, Huiqing, Reeves, Roger H, Blackshaw, Seth, Zhang, Jianying, Yu, Lianbo, Fernandez, Soledad A, Frankel, Wendy L, Bloomston, Mark, Rosol, Thomas J, Lesinski, Gregory B, Konieczny, Stephen F, Guttridge, Denis C, Rustgi, Anil K, Leone, Gustavo, Song, Jonathan W, Wu, Jinghai, Ostrowski, Michael C
Publicado no Life Sci Alliance (2018)

Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo

Por Caserta, Enrico, Egriboz, Onur, Wang, Hui, Martin, Chelsea, Koivisto, Christopher, Pecót, Thierry, Kladney, Raleigh D., Shen, Changxian, Shim, Kang-Sup, Pham, Thac, Karikomi, Matthew K., Mauntel, Melissa J., Majumder, Sarmila, Cuitino, Maria C., Tang, Xing, Srivastava, Arunima, Yu, Lianbo, Wallace, Julie, Mo, Xiaokui, Park, Morag, Fernandez, Soledad A., Pilarski, Robert, La Perle, Krista M.D., Rosol, Thomas J., Coppola, Vincenzo, Castrillon, Diego H., Timmers, Cynthia, Cohn, David E., O'Malley, David M., Backes, Floor, Suarez, Adrian A., Goodfellow, Paul, Chamberlin, Helen M., Macrae, Erin R., Shapiro, Charles L., Ostrowski, Michael C., Leone, Gustavo
Publicado no Genes Dev (2015)