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HYPOXIA-INDUCIBLE FACTOR-1α SUPPRESSES SQUAMOUS CARCINOGENIC PROGRESSION AND EPITHELIAL MESENCHYMAL TRANSITION
Hypoxia-inducible factor-1 is a known cancer progression factor, promoting growth, spread, and metastasis. However, in selected contexts HIF-1 is a tumor suppressor coordinating hypoxic cell cycle suppression and apoptosis. Prior studies focused on HIF-1 function in established malignancy, however l...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756430/ https://ncbi.nlm.nih.gov/pubmed/19276359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3643 |
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