Many-to-one comparisons after safety selection in multi-arm clinical trials

Por Hlavin, Gerald, Hampson, Lisa V., Koenig, Franz
Publicado no PLoS One (2017)

Efficacy and safety of FOLFIRINOX as salvage treatment in advanced biliary tract cancer: an open-label, single arm, phase 2 trial

Por Belkouz, Ali, de Vos-Geelen, Judith, Mathôt, Ron A. A., Eskens, Ferry A. L. M., van Gulik, Thomas M., van Oijen, Martijn G. H., Punt, Cornelis J. A., Wilmink, Johanna W., Klümpen, Heinz-Josef
Publicado no Br J Cancer (2020)

Safety and Pharmacokinetics of Intravenous Zanamivir Treatment in Hospitalized Adults With Influenza: An Open-label, Multicenter, Single-Arm, Phase II Study

Por Marty, Francisco M., Man, Choy Y., van der Horst, Charles, Francois, Bruno, Garot, Denis, Máňez, Rafael, Thamlikitkul, Visanu, Lorente, José A., Álvarez-Lerma, Francisco, Brealey, David, Zhao, Henry H., Weller, Steve, Yates, Phillip J., Peppercorn, Amanda F.
Publicado em 2014

Bivalent oral cholera vaccine in participants aged 1 year and older in the Dominican Republic: A phase III, single-arm, safety and immunogenicity trial

Por Cordero De Los Santos, Lina, Feris-Iglesias, Jesús, Aloysia D'Cor, Naveena, Midde, Venkata Jayanth, Patnaik, Badri Narayan, Thollot, Yaël, Rasuli, Anvar, Desauziers, Eric
Publicado no Hum Vaccin Immunother (2018)

Phase 1 safety assessment of intrathecal oxytocin

Por Eisenach, James C., Tong, Chuanyao, Curry, Regina
Publicado no Anesthesiology (2015)

Safety and efficacy of pulsed low-dose rate radiotherapy for local recurrent esophageal squamous...

Por Li, Jie, Zhao, Zhenhua, Du, Guobo, Dai, Tangzhi, Zhen, Xuhai, Cai, Hongwei, Liao, Dongbiao, Xiang, Miao, Wen, Yixue, Geng, Lidan, Yang, Xiyue, Feng, Gang, Zhang, Yu, Bai, Jie, Liu, Lei, Du, Xiaobo
Publicado no Medicine (Baltimore) (2019)

Intra- and postoperative catumaxomab in patients with epithelial ovarian cancer: safety and two-year efficacy results from a multicentre, single-arm, phase II study

Por Sehouli, J, Reinthaller, A, Marth, C, Reimer, D, Reimer, T, Stummvoll, W, Angleitner-Boubenizek, L, Brandt, B, Chekerov, R
Publicado em 2014

Efficacy and safety of Privigen® in patients with chronic inflammatory demyelinating polyneuropathy: results of a prospective, single-arm, open-label Phase III study (the PRIMA study)

Por Léger, Jean-Marc, De Bleecker, Jan L, Sommer, Claudia, Robberecht, Wim, Saarela, Mika, Kamienowski, Jerzy, Stelmasiak, Zbigniew, Mielke, Orell, Tackenberg, Björn, Shebl, Amgad, Bauhofer, Artur, Zenker, Othmar, Merkies, Ingemar S J
Publicado em 2013

A randomized, controlled trial comparing the efficacy and safety of aqueous subcutaneous...

Por Baker, Valerie L., Jones, Christopher A., Doody, Kevin, Foulk, Russell, Yee, Bill, Adamson, G. David, Cometti, Barbara, DeVane, Gary, Hubert, Gary, Trevisan, Silvia, Hoehler, Fred, Jones, Clarence, Soules, Michael
Publicado em 2014

Infliximab therapy for intestinal, neurological, and vascular involvement in Behcet disease: Efficacy, safety, and pharmacokinetics in a multicenter, prospective, open-label, single-arm phase 3 study

Por Hibi, Toshifumi, Hirohata, Shunsei, Kikuchi, Hirotoshi, Tateishi, Ukihide, Sato, Noriko, Ozaki, Kunihiko, Kondo, Kazuoki, Ishigatsubo, Yoshiaki
Publicado no Medicine (Baltimore) (2016)

P19.03 Randomized double arm phase III study to evaluate feasibility and safety of Gamma Knife...

Por Navarria, P., Ascolese, A., Cozzi, L., Tomatis, S., Picozzi, P., Pecchioli, G., Attuati, L., Clerici, E., Maggi, G., Scorsetti, M.
Publicado no Neuro Oncol (2016)

Single-Arm Nonrandomized Phase II study of Pazopanib in Patients with von Hippel-Lindau Disease

Por Jonasch, Eric, McCutcheon, Ian E., Gombos, Dan S., Ahrar, Kamran, Perrier, Nancy D., Liu, Diane, Robichaux, Christine C., Villarreal, Mercedes F., Weldon, Justin A., Woodson, Ashley H., Pilie, Patrick G., Fuller, Gregory N., Waguespack, Steven G., Matin, Surena F.
Publicado no Lancet Oncol (2018)

Study protocol for an open-label, single-arm, multicentre phase II trial to evaluate the efficacy...

Por Iihara, Hirotoshi, Shimokawa, Mototsugu, Abe, Masakazu, Hayasaki, Yoh, Fujita, Yukiyoshi, Nagasawa, Yuki, Sakurai, Michiru, Matsuoka, Rie, Suzuki, Akio, Morishige, Kenichiro
Publicado no BMJ Open (2019)

Efficacy and safety of buparlisib, a PI3K inhibitor, in patients with malignancies harboring a PI3K pathway activation: a phase 2, open-label, single-arm study

Por Piha-Paul, Sarina A., Taylor, Matthew H., Spitz, Daniel, Schwartzberg, Lee, Beck, J. Thaddeus, Bauer, Todd M., Meric-Bernstam, Funda, Purkayastha, Das, Karpiak, Linda, Szpakowski, Sebastian, Braiteh, Fadi
Publicado no Oncotarget (2019)

Ease of Use, Preference, and Safety of the Recombinant Human Growth Hormone Disposable Pen Compared with the Reusable Device: A Multicenter, Single-Arm, Open-Label, Switch-Over, Prospective, Phase IV Trial

Por Lee, Ji-Eun, Kim, Se Young, Yoo, Jae-Ho, Hwang, Il Tae, Lim, Jung Sub, Yi, Kyung Hee, Rhie, Young-Jun, Lee, Gyung Min, Nam, Hyo-Kyoung, Chae, Hyun Wook, Kim, Eun Young, Cheon, Chong Kun, Lee, Jieun, Shim, Young Suk, Lee, YuJin, Kim, Eun Young, Hwang, Jin Soon
Publicado no Patient Prefer Adherence (2019)

Apatinib in patients with extensive-stage small-cell lung cancer after second-line or third-line chemotherapy: a phase II, single-arm, multicentre, prospective study

Por Xu, Yanjun, Huang, Zhiyu, Lu, Hongyang, Yu, Xinming, Li, Yuping, Li, Wenfeng, Chen, Jun, Chen, Ming, Gong, Lei, Chen, Kaiyan, Qin, Jin, Xu, Xiaoling, Jin, Ying, Zhao, Jun, Shi, Xun, Han, Na, Xie, Fajun, Zhang, Peng, Xu, Weizhen, Fan, Yun
Publicado no Br J Cancer (2019)

Randomized Phase III Study to Assess Efficacy and Safety of Adjuvant CAPOX with or without...

Por Snoeren, Nikol, van Hillegersberg, Richard, Schouten, Sander B., Bergman, Andre M., van Werkhoven, Erikv, Dalesio, Otilia, Tollenaar, Rob A.E.M., Verheul, Henk M., van der Sijp, Joost, Borel Rinkes, Inne H.M., Voest, E.E.
Publicado no Neoplasia (2017)

Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial

Por Demetri, George D., von Mehren, Margaret, Jones, Robin L., Hensley, Martee L., Schuetze, Scott M., Staddon, Arthur, Milhem, Mohammed, Elias, Anthony, Ganjoo, Kristen, Tawbi, Hussein, Van Tine, Brian A., Spira, Alexander, Dean, Andrew, Khokhar, Nushmia Z., Park, Youn Choi, Knoblauch, Roland E., Parekh, Trilok V., Maki, Robert G., Patel, Shreyaskumar R.
Publicado no J Clin Oncol (2016)

P05.35 Intraoperative radiotherapy after resection of brain metastases (INTRAMET) - initial safety/efficacy analysis of a prospective phase II study

Por Brehmer, S, Welsch, M, Karakoyun, A, Förster, A, Seiz-Rosenhagen, M, Clausen, S, Schneider, F, Wenz, F, Hänggi, D, Giordano, F A
Publicado no Neuro Oncol (2018)

The efficacy and safety of CapeOX plus bevacizumab therapy followed by capecitabine plus...

Por Nakayama, Goro, Ishigure, Kiyoshi, Yokoyama, Hiroyuki, Uehara, Keisuke, Kojima, Hiroshi, Ishiyama, Akiharu, Hayashi, Naomi, Takano, Nao, Hattori, Norifumi, Kobayashi, Daisuke, Tanaka, Chie, Hayashi, Masamichi, Kanda, Mitsuro, Yamada, Suguru, Sugimoto, Hiroyuki, Koike, Masahiko, Fujiwara, Michitaka, Fujii, Tsutomu, Murotani, Kenta, Ando, Yuichi, Kodera, Yasuhiro
Publicado no BMC Cancer (2017)