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Phase 1 safety assessment of intrathecal oxytocin

BACKGROUND: Preclinical data suggest that oxytocin reduces hypersensitivity by actions in the spinal cord, but whether it produces antinociception to acute stimuli is unclear. Here we examined the safety of intrathecal oxytocin and screen its effects on acute noxious stimuli. METHODS: Following inst...

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Detalles Bibliográficos
Publicado en:Anesthesiology
Main Authors: Eisenach, James C., Tong, Chuanyao, Curry, Regina
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242190/
https://ncbi.nlm.nih.gov/pubmed/25502065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000539
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