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Preclinical toxicity screening of intrathecal oxytocin in rats and dogs

BACKGROUND: Anatomic, physiologic, and behavioral studies in animals suggest that spinally released oxytocin should produce analgesia in humans and may also protect from chronic pain after injury. Here we report preclinical toxicity screening of oxytocin for intrathecal delivery. METHODS: Intratheca...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Yaksh, Tony L., Hobo, Shotaro, Peters, Christopher, Osborn, Kent G., Richter, Philip J., Rossi, Steven S., Grafe, Marjorie R., Eisenach, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392224/
https://ncbi.nlm.nih.gov/pubmed/24492326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000148
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