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Intrathecal clonidine in the neonatal rat: dose-dependent analgesia and evaluation of spinal apoptosis and toxicity
BACKGROUND: Neuraxial clonidine is utilized for peri-operative analgesia in children of all ages. Preclinical studies in the postnatal rat allow comparison of the relative toxicity and safety of spinal analgesics throughout postnatal development. METHODS: Rat pups aged 3, 7 or 21 postnatal (P) days...
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| 出版年: | Anesth Analg |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4455964/ https://ncbi.nlm.nih.gov/pubmed/22467896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3182501a09 |
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