Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial

PURPOSE: This multicenter study, to our knowledge, is the first phase III trial to compare trabectedin versus dacarbazine in patients with advanced liposarcoma or leiomyosarcoma after prior therapy with an anthracycline and at least one additional systemic regimen. PATIENTS AND METHODS: Patients wer...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Demetri, George D., von Mehren, Margaret, Jones, Robin L., Hensley, Martee L., Schuetze, Scott M., Staddon, Arthur, Milhem, Mohammed, Elias, Anthony, Ganjoo, Kristen, Tawbi, Hussein, Van Tine, Brian A., Spira, Alexander, Dean, Andrew, Khokhar, Nushmia Z., Park, Youn Choi, Knoblauch, Roland E., Parekh, Trilok V., Maki, Robert G., Patel, Shreyaskumar R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2016
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070559/
https://ncbi.nlm.nih.gov/pubmed/26371143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.62.4734
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