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Many-to-one comparisons after safety selection in multi-arm clinical trials

In phase II platform trials, ‘many-to-one’ comparisons are performed when K experimental treatments are compared with a common control to identify the most promising treatment(s) to be selected for Phase III trials. However, when sample sizes are limited, such as when the disease of interest is rare...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Hlavin, Gerald, Hampson, Lisa V., Koenig, Franz
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484516/
https://ncbi.nlm.nih.gov/pubmed/28651023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180131
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