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Designing multi‐arm multi‐stage clinical trials using a risk–benefit criterion for treatment selection

Multi‐arm clinical trials that compare several active treatments to a common control have been proposed as an efficient means of making an informed decision about which of several treatments should be evaluated further in a confirmatory study. Additional efficiency is gained by incorporating interim...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Jaki, Thomas, Hampson, Lisa V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950037/
https://ncbi.nlm.nih.gov/pubmed/26456537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6760
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