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An order restricted multi‐arm multi‐stage clinical trial design

One family of designs that can noticeably improve efficiency in later stages of drug development are multi‐arm multi‐stage (MAMS) designs. They allow several arms to be studied concurrently and gain efficiency by dropping poorly performing treatment arms during the trial as well as by allowing to st...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Serra, Alessandra, Mozgunov, Pavel, Jaki, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612618/
https://ncbi.nlm.nih.gov/pubmed/35048391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.9314
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