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An order restricted multi‐arm multi‐stage clinical trial design

One family of designs that can noticeably improve efficiency in later stages of drug development are multi‐arm multi‐stage (MAMS) designs. They allow several arms to be studied concurrently and gain efficiency by dropping poorly performing treatment arms during the trial as well as by allowing to st...

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Bibliografiske detaljer
Udgivet i:Stat Med
Main Authors: Serra, Alessandra, Mozgunov, Pavel, Jaki, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2022
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612618/
https://ncbi.nlm.nih.gov/pubmed/35048391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.9314
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