Resultados da pesquisa - (( j ras camp c new ) OR ((( _ nay clamp

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A yeast homologue of the bovine lens fibre MIP gene family complements the growth defect of a Saccharomyces cerevisiae mutant on fermentable sugars but not its defect in glucose-induced RAS-mediated cAMP...

Por Van Aelst, L, Hohmann, S, Zimmermann, F K, Jans, A W, Thevelein, J M
Publicado em 1991

“.... The deficiency of the fdp1 mutant in glucose-induced RAS-mediated cAMP signalling and in rapid glucose-induced...”
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Amino acid transport through the Saccharomyces cerevisiae Gap1 permease is controlled by the Ras/cAMP pathway

Por Garrett, Jinnie M.
Publicado em 2007

“... sources of nitrogen in the surrounding medium. Yeast with an activated Ras2/cAMP pathway show many...”
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Ras Protein/cAMP-dependent Protein Kinase Signaling Is Negatively Regulated by a Deubiquitinating Enzyme, Ubp3, in Yeast

Por Li, Yang, Wang, Yuqi
Publicado em 2013

“...Ras proteins and cAMP-dependent protein kinase (protein kinase A, PKA) are important components...”
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Guanine nucleotide exchange factor Epac2–dependent activation of the GTP-binding protein Rap2A mediates cAMP-dependent growth arrest in neuroendocrine cells

Por Emery, Andrew C., Xu, Wenqin, Eiden, Maribeth V., Eiden, Lee E.
Publicado no J Biol Chem (2017)

“.... Three cAMP sensors, Epac2, PKA, and neuritogenic cAMP sensor–Rapgef2, mediate distinct cellular outputs...”
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CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response

Por Dixon, Zach A., Nicholson, Lindsay, Zeppetzauer, Martin, Matheson, Elizabeth, Sinclair, Paul, Harrison, Christine J., Irving, Julie A.E.
Publicado no Haematologica (2017)

“... acetylation of histone 3 lysine 18, but has no significant impact on cAMP-dependent target gene expression...”
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Cell physiology of cAMP sensor Epac

Por Holz, George G, Kang, Guoxin, Harbeck, Mark, Roe, Michael W, Chepurny, Oleg G
Publicado em 2006

“... of the Ras family. By activating Rap in an Epac-mediated manner, cAMP influences diverse cellular processes...”
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Dopamine Induces a PI3-Kinase-Independent Activation of Akt in Striatal Neurons: A New Route to cAMP Response Element-Binding Protein Phosphorylation

Por Brami-Cherrier, Karen, Valjent, Emmanuel, Garcia, Marta, Pagès, Christiane, Hipskind, Robert A., Caboche, Jocelyne
Publicado no J Neurosci (2002)

“..., overexpression of a mutant form of Akt that cannot be activated impaired cAMP response element-binding protein...”
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Evidence for a role of rap1 protein in the regulation of human platelet Ca2+ fluxes.

Por Corvazier, E, Enouf, J, Papp, B, de Gunzburg, J, Tavitian, A, Levy-Toledano, S
Publicado em 1992

“...The relationship between the 22-24 kDa cyclic AMP (cAMP)-dependent phosphoprotein previously...”
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Ksp1 Kinase Regulates Autophagy via the Target of Rapamycin Complex 1 (TORC1) Pathway

Por Umekawa, Midori, Klionsky, Daniel J.
Publicado em 2012

“... activated by the Ras/cAMP-dependent protein kinase A (PKA), which is another negative regulator of autophagy...”
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Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation

Por Wang, Zhiping, Dillon, Tara J., Pokala, Viji, Mishra, Snigdha, Labudda, Kirstin, Hunter, Brian, Stork, Philip J. S.
Publicado em 2006

“... membrane. In this new locale it is capable of activating ERKs in a Rap1- and cAMP-dependent manner. Rap1...”
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The EPAC–Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability

Por Ramos, Carla J., Lin, Chengmao, Liu, Xuwen, Antonetti, David A.
Publicado no J Biol Chem (2018)

“... vascular permeability and restore the blood–retinal barrier (BRB) may lead to new therapies. The cAMP...”
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Neurofibromatosis Type 1: Modeling CNS Dysfunction

Por Gutmann, David H., Parada, Luis F., Silva, Alcino J., Ratner, Nancy
Publicado em 2012

“... meeting, that highlight unexpected cell biology insights into RAS and cAMP pathway effects on neural...”
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Mutual Interdependence of MSI1 (CAC3) and YAK1 in Saccharomyces cerevisiae

Por Pratt, Zachary L., Drehman, Bethany J., Miller, Mary E., Johnston, Stephen D.
Publicado em 2007

“... including suppression of the RAS/cAMP/Protein Kinase A signaling pathway, chromatin assembly...”
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Delineating the core regulatory elements crucial for directed cell migration by examining folic-acid-mediated responses

Por Srinivasan, Kamalakkannan, Wright, Gus A., Hames, Nicole, Housman, Max, Roberts, Alayna, Aufderheide, Karl J., Janetopoulos, Chris
Publicado em 2013

“..., and towards cAMP during development. We determined the spatiotemporal localization of cytoskeletal...”
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Epidermal growth factor receptor controls glycogen phosphorylase in T cells through small GTPases of the RAS family

Por Llavero, Francisco, Luque Montoro, Miriam, Arrazola Sastre, Alazne, Fernández-Moreno, David, Lacerda, Hadriano M., Parada, Luis A., Lucia, Alejandro, Zugaza, José L.
Publicado no J Biol Chem (2019)

“... exchange protein directly activated by cAMP 2 (EPAC2) and RAP1 via RAS and ADCY6 phosphorylation...”
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Yeast cdc35 mutants are defective in adenylate cyclase and are allelic with cyr1 mutants while CAS1, a new gene, is involved in the regulation of adenylate cyclase.

Por Boutelet, F, Petitjean, A, Hilger, F
Publicado em 1985

“... start mutants. The cdc35 mutation induces a significant decrease of the intracellular cAMP level...”
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Role of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiology

Por Yang, Shi-kun, Xiao, Li, Li, Jun, Liu, Fuyou, Sun, Lin, Kanwar, Yashpal S.
Publicado em 2013

“... as new sensors for the second messenger cAMP. The Epac family members, including Epac1 and Epac2...”
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β-Amyloid Peptide at Sublethal Concentrations Downregulates Brain-Derived Neurotrophic Factor Functions in Cultured Cortical Neurons

Por Tong, Liqi, Balazs, Robert, Thornton, Phillip L., Cotman, Carl W.
Publicado no J Neurosci (2004)

“... in the suppression of the activation of critical transcription factor cAMP response element-binding protein and Elk-1...”
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The membrane trafficking and functionality of the K(+)-Cl(−) co-transporter KCC2 is regulated by TGF-β2

Por Roussa, Eleni, Speer, Jan Manuel, Chudotvorova, Ilona, Khakipoor, Shokoufeh, Smirnov, Sergei, Rivera, Claudio, Krieglstein, Kerstin
Publicado no J Cell Sci (2016)

“... TGF-β2 to cAMP-response-element-binding protein (CREB) and Ras-associated binding protein 11b (Rab11b...”
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Induction and mitochondrial localization of cytochrome P450scc system enzymes in normal and transformed ovarian granulosa cells

Publicado em 1990

“... oncogene. In these cells progesterone secretion can be induced by cAMP as in normal rat granulosa cells...”
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