Epidermal growth factor receptor controls glycogen phosphorylase in T cells through small GTPases of the RAS family

We recently uncovered a regulatory pathway of the muscle isoform of glycogen phosphorylase (PYGM) that plays an important role in regulating immune function in T cells. Here, using various enzymatic, pulldown, and immunoprecipitation assays, we describe signaling cross-talk between the small GTPases...

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Vydáno v:J Biol Chem
Hlavní autoři: Llavero, Francisco, Luque Montoro, Miriam, Arrazola Sastre, Alazne, Fernández-Moreno, David, Lacerda, Hadriano M., Parada, Luis A., Lucia, Alejandro, Zugaza, José L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433075/
https://ncbi.nlm.nih.gov/pubmed/30647127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005997
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