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Role of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiology
Exchange proteins directly activated by cAMP [Epac(s)] were discovered more than a decade ago as new sensors for the second messenger cAMP. The Epac family members, including Epac1 and Epac2, are guanine nucleotide exchange factors for the Ras-like small GTPases Rap1 and Rap2, and they function inde...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625846/ https://ncbi.nlm.nih.gov/pubmed/23364803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00711.2012 |
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