Resultados da pesquisa - (( j nart chirp can ngoc ) OR ((( j a clamp i now ) OR ( j et comp balao ngoc ))))

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Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp

Por Verkerk, Arie O., Veerman, Christiaan C., Zegers, Jan G., Mengarelli, Isabella, Bezzina, Connie R., Wilders, Ronald
Publicado no Int J Mol Sci (2017)

“... reproducible dynamic clamp approach to provide these cells with a substantial I(K1) (computed in real time...”
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The human checkpoint sensor and alternative DNA clamp Rad9–Rad1–Hus1 modulates the activity of DNA...

Por Smirnova, Ekaterina, Toueille, Magali, Markkanen, Enni, Hübscher, Ulrich
Publicado em 2005

“...The human checkpoint sensor and alternative clamp Rad9–Rad1–Hus1 can interact with and specifically...”
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Using computer simulations to determine the limitations of dynamic clamp stimuli applied at the soma in mimicking distributed conductance sources

Por Lin, Risa J., Jaeger, Dieter
Publicado em 2011

“...In previous studies we used the technique of dynamic clamp to study how temporal modulation...”
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Isoform-specific regulation of the sodium pump by α- and β-adrenergic agonists in the guinea-pig ventricle

Por Gao, J, Wymore, R, Wymore, R T, Wang, Y, McKinnon, D, Dixon, J E, Mathias, R T, Cohen, I S, Baldo, G J
Publicado em 1999

“... protein kinase A (PKA)-dependent pathway. We now show that these β-effects are targeted to the α(1...”
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NeuReal: an interactive simulation system for implementing artificial dendrites and large hybrid networks

Por Hughes, Stuart W., Lörincz, Magor, Cope, David W., Crunelli, Vincenzo
Publicado em 2007

“...The dynamic clamp is a technique which allows the introduction of artificial conductances...”
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Small-Fiber Neuropathy Na(v)1.8 Mutation Shifts Activation to Hyperpolarized Potentials and Increases Excitability of Dorsal Root Ganglion Neurons

Por Huang, Jianying, Yang, Yang, Zhao, Peng, Gerrits, Monique M., Hoeijmakers, Janneke G.J ., Bekelaar, Kim, Merkies, Ingemar S.J., Faber, Catharina G., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Publicado no J Neurosci (2013)

“... hyperexcitable, in I-SFN patients with no mutations of SCN9A. We have now evaluated additional I-SFN patients...”
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Open channel noise. I. Noise in acetylcholine receptor currents suggests conformational fluctuations.

Por Sigworth, F J
Publicado em 1985

“... in the channel current. The patch-clamp technique now allows fluctuations of this size to be observed in single...”
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Lipopolysaccharide prolongs action potential duration in HL-1 mouse cardiomyocytes

Por Wondergem, Robert, Graves, Bridget M., Li, Chuanfu, Williams, David L.
Publicado em 2012

“...+) regulation and by impairing pacemaker “funny” current, I(f). We now explore further cellular mechanisms...”
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Structure of Ca(2+) Release Channel at 14 Å Resolution

Por Serysheva, Irina I., Hamilton, Susan L., Chiu, Wah, Ludtke, Steven J.
Publicado em 2005

“...The 14 Å resolution structure of the 2.3 MDa Ca(2+) release channel (also known as RyR1...”
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Anion currents in yeast K(+) transporters (TRK) characterize a structural homologue of ligand-gated ion channels

Por Rivetta, Alberto, Kuroda, Teruo, Slayman, Clifford
Publicado em 2011

“...Patch clamp studies of the potassium-transport proteins TRK1,2 in Saccharomyces cerevisiae have...”
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A web portal for in-silico action potential predictions

Por Williams, Geoff, Mirams, Gary R.
Publicado no J Pharmacol Toxicol Methods (2015)

“... can now be measured in automated patch clamp screening assays. In-silico action potential models...”
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Inhibition of serine/threonine protein phosphatases promotes opening of voltage-activated L-type Ca2+ channels in insulin-secreting cells.

Por Haby, C, Larsson, O, Islam, M S, Aunis, D, Berggren, P O, Zwiller, J
Publicado em 1994

“...+ and was abolished by D600, a blocker of voltage-activated L-type Ca2+ channels. Concomitant with the rise in [Ca2+]i...”
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Development of a lung slice preparation for recording ion channel activity in alveolar epithelial type I cells

Por Bourke, Steven, Mason, Helen S, Borok, Zea, Kim, Kwang-Jin, Crandall, Edward D, Kemp, Paul J
Publicado em 2005

“... alveolar type I cells to be recorded using the cell-attached configuration of the patch-clamp technique...”
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Liver Transplantation in Man—II, a Report of two Orthotopic Liver Transplants in Adult Recipients

Por Calne, R. Y., Williams, Roger, Dawson, J. L., Ansell, I. D., Evans, D. B., Flute, P. T., Herbertson, P. M., Joysey, V., Keates, G. H. W., Knill-Jones, R. P., Mason, S. A., Millard, P. R., Pena, J. R., Pentlow, B. D., Salaman, J. R., Sells, R. A., Cullum, P. A.
Publicado em 1968

“... of the arterial clamp. In an attempt to control the growth before transplantation, the patient had been treated...”
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Developmental changes in the expression of potassium currents of embryonic, neonatal and mature mouse inner hair cells

Por Marcotti, Walter, Johnson, Stuart L, Holley, Matthew C, Kros, Corné J
Publicado em 2003

“... that is largely insensitive to 4-aminopyridine (4-AP). One day later the inward rectifier, I(K1), is first...”
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Phosphodiesterase 5 Restricts NOS3/Soluble Guanylate Cyclase signaling to L-type Ca(2+) current in Cardiac Myocytes

Por Wang, Honglan, Kohr, Mark J, Traynham, Christopher J, Ziolo, Mark T
Publicado em 2009

“... amplitudes in WT myocytes. The effects of YC-1 on I(Ca) and cardiac contraction were blocked by KT5823 (a...”
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Calcium Current Activated by Depletion of Calcium Stores in Xenopus Oocytes

Por Yao, Yong, Tsien, Roger Y.
Publicado em 1997

“... and the distortions in measuring I(Cl(Ca)) can now be bypassed, oocytes are now a superior system in which to analyze...”
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A Long-Lasting Calcium-Activated Nonselective Cationic Current Is Generated by Synaptic Stimulation or Exogenous Activation of Group I Metabotropic Glutamate Receptors in CA1 Pyramidal Neurons

Por Congar, Patrice, Leinekugel, Xavier, Ben-Ari, Yehezkel, Crépel, Valérie
Publicado no J Neurosci (1997)

“... characterized as a Ca(2+)-activated nonselective cationic (CAN) current. Using whole-cell patch-clamp recordings...”
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Developmental regulation of membrane excitability in rat spinal lamina I projection neurons

Por Li, Jie, Baccei, Mark L.
Publicado em 2012

“...It is now universally recognized that neonates can experience considerable pain. While spinal...”
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Gα(i3) primes the G protein-activated K(+) channels for activation by coexpressed Gβγ in intact Xenopus oocytes

Por Rubinstein, Moran, Peleg, Sagit, Berlin, Shai, Brass, Dovrat, Dascal, Nathan
Publicado em 2007

“... than a mere Gβγ donor. We have proposed that Gα(i3)–GDP regulates GIRK gating, keeping its basal...”
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