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Lipopolysaccharide prolongs action potential duration in HL-1 mouse cardiomyocytes

Sepsis has deleterious effects on cardiac function including reduced contractility. We have shown previously that lipopolysaccharides (LPS) directly affect HL-1 cardiac myocytes by inhibiting Ca(2+) regulation and by impairing pacemaker “funny” current, I(f). We now explore further cellular mechanis...

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Detalhes bibliográficos
Main Authors: Wondergem, Robert, Graves, Bridget M., Li, Chuanfu, Williams, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469715/
https://ncbi.nlm.nih.gov/pubmed/22895260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00173.2012
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