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Lipopolysaccharide prolongs action potential duration in HL-1 mouse cardiomyocytes
Sepsis has deleterious effects on cardiac function including reduced contractility. We have shown previously that lipopolysaccharides (LPS) directly affect HL-1 cardiac myocytes by inhibiting Ca(2+) regulation and by impairing pacemaker “funny” current, I(f). We now explore further cellular mechanis...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3469715/ https://ncbi.nlm.nih.gov/pubmed/22895260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00173.2012 |
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