Patch-Clamp Recording from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Improving Action Potential Characteristics through Dynamic Clamp

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) hold great promise for studying inherited cardiac arrhythmias and developing drug therapies to treat such arrhythmias. Unfortunately, until now, action potential (AP) measurements in hiPSC-CMs have been hampered by the virtual ab...

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Pubblicato in:Int J Mol Sci
Autori principali: Verkerk, Arie O., Veerman, Christiaan C., Zegers, Jan G., Mengarelli, Isabella, Bezzina, Connie R., Wilders, Ronald
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618522/
https://ncbi.nlm.nih.gov/pubmed/28867785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091873
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