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Patch-Clamp Recordings of Action Potentials From Human Atrial Myocytes: Optimization Through Dynamic Clamp

Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia. Consequently, novel therapies are being developed. Ultimately, the impact of compounds on the action potential (AP) needs to be tested in freshly isolated human atrial myocytes. However, the frequent depolarized state of t...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Verkerk, Arie O., Marchal, Gerard A., Zegers, Jan G., Kawasaki, Makiri, Driessen, Antoine H. G., Remme, Carol Ann, de Groot, Joris R., Wilders, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072333/
https://ncbi.nlm.nih.gov/pubmed/33912059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.649414
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