Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual I(K1)

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are widely used in studying basic mechanisms of cardiac arrhythmias that are caused by ion channelopathies. Unfortunately, the action potential profile of hiPSC-CMs—and consequently the profile of individual membrane currents act...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Meijer van Putten, Rosalie M. E., Mengarelli, Isabella, Guan, Kaomei, Zegers, Jan G., van Ginneken, Antoni C. G., Verkerk, Arie O., Wilders, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315032/
https://ncbi.nlm.nih.gov/pubmed/25691870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00007
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