HERG Channel (Dys)function Revealed by Dynamic Action Potential Clamp Technique

The human ether-a-go-go-related gene (HERG) encodes the rapid component of the cardiac delayed rectifier potassium current (I(Kr)). Per-Arnt-Sim domain mutations of the HERG channel are linked to type 2 long-QT syndrome. We studied wild-type and/or type 2 long-QT syndrome-associated mutant (R56Q) HE...

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Main Authors: Berecki, Géza, Zegers, Jan G., Verkerk, Arie O., Bhuiyan, Zahurul A., de Jonge, Berend, Veldkamp, Marieke W., Wilders, Ronald, van Ginneken, Antoni C. G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2005
Ábhair:
Spectroscopy, Imaging, Other Techniques
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305034/
https://ncbi.nlm.nih.gov/pubmed/15475579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.047290
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