Resultados da pesquisa - (( j m cooper jason a ) OR ((( a two coupled trans ngoc ) OR ( 3.5 nacl najar marcos rogerio ))))

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Modeling Parkinson’s Disease in C. elegans

Por Cooper, Jason F., Van Raamsdonk, Jeremy M.
Publicado no J Parkinsons Dis (2018)

“..., and worms with deletions in PRKN/pdr-1, PINK1/pink-1, DJ-1/djr-1.1/djr-1.2 and ATP13A2/catp-6. These worms...”
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Variation in serum biomarkers with sex and female hormonal status: implications for clinical tests

Por Ramsey, Jordan M., Cooper, Jason D., Penninx, Brenda W. J. H., Bahn, Sabine
Publicado no Sci Rep (2016)

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Suppression of statin effectiveness by copper and zinc in yeast and human cells

Por Fowler, Douglas M., Cooper, Sara J., Stephany, Jason J., Hendon, Natalie, Nelson, Sven, Fields, Stanley
Publicado em 2010

“...Lovastatin and other statins inhibit HMG-CoA reductase, which carries out an early step...”
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Identification of Mycobacteria by Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry

Por Pignone, Michelle, Greth, Kimberly M., Cooper, Jason, Emerson, David, Tang, Jane
Publicado em 2006

“... profiles. Speciation of a Mycobacterium isolate using these standard methods is a lengthy process based...”
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A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

Por Kalsotra, Auinash, Xiao, Xinshu, Ward, Amanda J., Castle, John C., Johnson, Jason M., Burge, Christopher B., Cooper, Thomas A.
Publicado em 2008

“...From a large-scale screen using splicing microarrays and RT-PCR, we identified 63 alternative...”
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Delaying aging is neuroprotective in Parkinson’s disease: a genetic analysis in C. elegans models

Por Cooper, Jason F, Dues, Dylan J, Spielbauer, Katie K, Machiela, Emily, Senchuk, Megan M, Van Raamsdonk, Jeremy M
Publicado no NPJ Parkinsons Dis (2015)

“... crossed transgenic worm models of PD expressing either human mutant α-synuclein (A53T) or LRRK2 (G2019...”
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Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson’s disease models

Por Cooper, Jason F., Machiela, Emily, Dues, Dylan J., Spielbauer, Katie K., Senchuk, Megan M., Van Raamsdonk, Jeremy M.
Publicado no Sci Rep (2017)

“... dysfunction is thought to play a crucial role in disease pathogenesis. Here, we examined the relationship...”
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FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection

Por Smyth, Deborah J., Cooper, Jason D., Howson, Joanna M.M., Clarke, Pamela, Downes, Kate, Mistry, Trupti, Stevens, Helen, Walker, Neil M., Todd, John A.
Publicado em 2011

“...(−18)), based on a recessive effects model. CONCLUSIONS: Our findings linking FUT2 and type 1 diabetes...”
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Whole Genome Sequence Analysis of the First Australian OXA-48-Producing Outbreak-Associated Klebsiella pneumoniae Isolates: The Resistome and In Vivo Evolution

Por Espedido, Björn A., Steen, Jason A., Ziochos, Helen, Grimmond, Sean M., Cooper, Matthew A., Gosbell, Iain B., van Hal, Sebastiaan J., Jensen, Slade O.
Publicado em 2013

“..., the carbapenem-hydrolyzing β-lactamase gene bla (OXA-48) and the extended-spectrum β-lactamase gene bla (CTX-M-14...”
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Factors Influencing Blood Pressure Response to Trandolapril Add-On Therapy in Patients Taking Verapamil SR (from the International Verapamil SR/Trandolapril [INVEST] Study)

Por Brunner, Martin, Cooper-DeHoff, Rhonda M., Gong, Yan, Karnes, Jason H., Langaee, Taimour Y., Pepine, Carl J., Johnson, Julie A.
Publicado em 2007

“..., the association with a polymorphism (1166A→C) in the angiotensin II type 1 receptor gene (AGTR1) was tested. BP...”
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Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes

Por Cooper, Nicholas J., Shtir, Corina J., Smyth, Deborah J., Guo, Hui, Swafford, Austin D., Zanda, Manuela, Hurles, Matthew E., Walker, Neil M., Plagnol, Vincent, Cooper, Jason D., Howson, Joanna M.M., Burren, Oliver S., Onengut-Gumuscu, Suna, Rich, Stephen S., Todd, John A.
Publicado no Hum Mol Genet (2015)

“...Copy number variants (CNVs) have been proposed as a possible source of ‘missing heritability...”
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Directional Optical Coherence Tomography Provides Accurate Outer Nuclear Layer and Henle Fiber Layer Measurements

Por Lujan, Brandon J., Roorda, Austin, Croskrey, Jason A., Dubis, Adam M., Cooper, Robert F., Bayabo, Jan-Kristine, Duncan, Jacque L., Antony, Bhavna J., Carroll, Joseph
Publicado no Retina (2015)

“... of the ONL and HFL boundary is made possible by using Directional OCT (D-OCT), a method that purposefully...”
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α-synuclein expression from a single copy transgene increases sensitivity to stress and accelerates neuronal loss in genetic models of Parkinson’s disease

Por Cooper, Jason F., Spielbauer, Katie K., Senchuk, Megan M., Nadarajan, Saravanapriah, Colaiácovo, Monica P., Van Raamsdonk, Jeremy M.
Publicado no Exp Neurol (2018)

“... on phenotypic deficits in PD deletion mutants affecting PARK2/pdr-1, PINK1/pink-1, DJ-1/djr-1.1 and ATP13A2/catp...”
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IMPACT OF TCF7L2 SINGLE NUCLEOTIDE POLYMORPHISMS ON HYDROCHLOROTHIAZIDE-INDUCED DIABETES

Por Karnes, Jason H, Gong, Yan, Pacanowski, Michael A, McDonough, Caitrin W, Arwood, Meghan J, Langaee, Taimour Y, Pepine, Carl J, Johnson, Julie A, Cooper-DeHoff, Rhonda M
Publicado em 2013

“...7917983 (synergy index 3.37 [95%CI 1.72–6.59], p=5.0×10(−4), P(ACT) =0.03), which was associated...”
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Alteration in Fasting Glucose after Prolonged Treatment with a Thiazide Diuretic

Por Karnes, Jason H, Gong, Yan, Arwood, Meghan J, Gums, John G, Hall, Karen, Limacher, Marian C, Johnson, Julie A, Cooper-DeHoff, Rhonda M
Publicado em 2014

“... of thiazide treatment. FG increased 6.5 (SD 13.0) mg/dL during short-term thiazide treatment and 3.6 (SD 15.3...”
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In vivo evolution of antimicrobial resistance in a series of Staphylococcus aureus patient isolates: the entire picture or a cautionary tale?

Por van Hal, Sebastiaan J., Steen, Jason A., Espedido, Björn A., Grimmond, Sean M., Cooper, Matthew A., Holden, Matthew T. G., Bentley, Stephen D., Gosbell, Iain B., Jensen, Slade O.
Publicado em 2014

“...-resistant Staphylococcus aureus blood culture isolates (ST239-MRSA-III) from a single patient exposed...”
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Feasibility of a Nonoperative Management Strategy for Uncomplicated Acute Appendicitis in Children

Por Minneci, Peter C, Sulkowski, Jason P, Nacion, Kristine M, Mahida, Justin B, Cooper, Jennifer N, Moss, R. Lawrence, Deans, Katherine J
Publicado em 2014

“... days (3 vs. 17 days, p<0.0001), returned to school more quickly (3 vs. 5 days, p=0.008), and exhibited...”
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The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes

Por Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Payne, Felicity, Downes, Kate, Godfrey, Lisa M, Masters, Jennifer, Zeitels, Lauren R, Vella, Adrian, Walker, Neil M, Todd, John A
Publicado em 2007

“... of being associated with other immune-mediated diseases, we tested three such genes, IL23R, IRF5 and CD40...”
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Seven newly identified loci for autoimmune thyroid disease

Por Cooper, Jason D., Simmonds, Matthew J., Walker, Neil M., Burren, Oliver, Brand, Oliver J., Guo, Hui, Wallace, Chris, Stevens, Helen, Coleman, Gillian, Franklyn, Jayne A., Todd, John A., Gough, Stephen C.L.
Publicado em 2012

“... determinants of AITD, we conducted an association study using a custom-made single-nucleotide polymorphism (SNP...”
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Sex Differences in Serum Markers of Major Depressive Disorder in the Netherlands Study of Depression and Anxiety (NESDA)

Por Ramsey, Jordan M., Cooper, Jason D., Bot, Mariska, Guest, Paul C., Lamers, Femke, Weickert, Cynthia S., Penninx, Brenda W. J. H., Bahn, Sabine
Publicado no PLoS One (2016)

“... in immune response, including C-reactive protein, trefoil factor 3, cystatin-C, fetuin-A, β2-microglobulin...”
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