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A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

From a large-scale screen using splicing microarrays and RT-PCR, we identified 63 alternative splicing (AS) events that are coordinated in 3 distinct temporal patterns during mouse heart development. More than half of these splicing transitions are evolutionarily conserved between mouse and chicken....

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Detalhes bibliográficos
Main Authors: Kalsotra, Auinash, Xiao, Xinshu, Ward, Amanda J., Castle, John C., Johnson, Jason M., Burge, Christopher B., Cooper, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629332/
https://ncbi.nlm.nih.gov/pubmed/19075228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809045105
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