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Suppression of statin effectiveness by copper and zinc in yeast and human cells
Lovastatin and other statins inhibit HMG-CoA reductase, which carries out an early step in the sterol biosynthesis pathway. Statins lower cholesterol and are widely prescribed to prevent heart disease, but like many drugs, they can interact with nutritionally acquired metabolites. To probe these int...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138400/ https://ncbi.nlm.nih.gov/pubmed/21085730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mb00166j |
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