Resultados da pesquisa - (( j l (compr OR comer) a newly ) OR ((( 5 natl complex can now ) OR ( l name company cpr now ))))*

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1

Synthesis
of a Bicyclic Azetidine with In Vivo Antimalarial Activity Enabled
by Stereospecific, Directed C(sp(3))–H Arylation

Synthesis of a Bicyclic Azetidine with In Vivo Antimalarial Activity Enabled by Stereospecific, Directed C(sp(3))–H Arylation

Por Maetani, Micah, Zoller, Jochen, Melillo, Bruno, Verho, Oscar, Kato, Nobutaka, Pu, Jun, Comer, Eamon, Schreiber, Stuart L.
Publicado no J Am Chem Soc (2017)

“... three stages of the parasite’s life cycle, but a lengthy synthetic route to these compounds may affect...”
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2

Chapare Virus, a Newly Discovered Arenavirus Isolated from a Fatal Hemorrhagic Fever Case in Bolivia

Chapare Virus, a Newly Discovered Arenavirus Isolated from a Fatal Hemorrhagic Fever Case in Bolivia

Por Delgado, Simon, Erickson, Bobbie R., Agudo, Roberto, Blair, Patrick J., Vallejo, Efrain, Albariño, César G., Vargas, Jorge, Comer, James A., Rollin, Pierre E., Ksiazek, Thomas G., Olson, James G., Nichol, Stuart T.
Publicado em 2008

“... the virus represents a newly discovered arenavirus, for which we propose the name Chapare virus...”
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3

Documentation of fertility preservation discussions for young adults with cancer: Examining compliance with treatment guidelines

Documentation of fertility preservation discussions for young adults with cancer: Examining compliance with treatment guidelines

Por Salsman, John M., Yanez, Betina, Smith, Kristin N., Beaumont, Jennifer L., Snyder, Mallory A., Barnes, Khouri, Clayman, Marla L.
Publicado no J Natl Compr Canc Netw (2016)

“... and newly diagnosed young adults with cancer about the possibility of cancer treatment-related infertility...”
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4

Impact of a Clinical Trial Initiative on Clinical Trial Enrollment in a Multidisciplinary Prostate Cancer Clinic

Impact of a Clinical Trial Initiative on Clinical Trial Enrollment in a Multidisciplinary Prostate Cancer Clinic

Por Madsen, Lydia T., Kuban, Deborah A., Choi, Seungtaek, Davis, John W., Kim, Jeri, Lee, Andrew K., Domain, Delora, Levy, Larry, Pisters, Louis L., Pettaway, Curtis A., Ward, John F., Logothetis, Christopher, Hoffman, Karen E.
Publicado no J Natl Compr Canc Netw (2014)

“...PURPOSE: Clinical oncology trials are hampered by low accrual rates with less than 5% of adult...”
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5

Hodgkin Lymphoma, Version 2.2015: Clinical Practice Guidelines in Oncology

Hodgkin Lymphoma, Version 2.2015: Clinical Practice Guidelines in Oncology

Por Hoppe, Richard T., Advani, Ranjana H., Ai, Weiyun Z., Ambinder, Richard F., Aoun, Patricia, Bello, Celeste M., Benitez, Cecil M., Bierman, Philip J., Blum, Kristie A., Chen, Robert, Dabaja, Bouthaina, Forero, Andres, Gordon, Leo I., Hernandez-Ilizaliturri, Francisco J., Hochberg, Ephraim P., Huang, Jiayi, Johnston, Patrick B., Khan, Nadia, Maloney, David G., Mauch, Peter M., Metzger, Monika, Moore, Joseph O., Morgan, David, Moskowitz, Craig H., Mulroney, Carolyn, Poppe, Matthew, Rabinovitch, Rachel, Seropian, Stuart, Tsien, Christina, Winter, Jane N., Yahalom, Joachim, Burns, Jennifer L., Sundar, Hema
Publicado no J Natl Compr Canc Netw (2015)

“... therapy, followed by restaging with PET/CT to assess treatment response using the Deauville criteria (5...”
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6

Phosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusion

Phosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusion

Por Mima, Joji, Wickner, William
Publicado em 2009

“... complex), and 2 phosphoinositides, phosphatidylinositol 3-phosphate [PI(3)P] and phosphatidylinositol 4,5...”
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7

Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway.

Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway.

Por Davis, L I, Blobel, G
Publicado em 1987

“... specifically to wheat germ agglutinin. Therefore, we proposed that this nuclear pore complex protein might be a...”
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8

The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes

The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes

Por Balderhaar, Henning J. kleine, Lachmann, Jens, Yavavli, Erdal, Bröcker, Cornelia, Lürick, Anna, Ungermann, Christian
Publicado em 2013

“... and function. Until now, despite the absence of experimental evidence, it has been assumed that CORVET is a...”
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9

Inositol hexakisphosphate stimulates non-Ca(2+)-mediated and primes Ca(2+)-mediated exocytosis of insulin by activation of protein kinase C

Inositol hexakisphosphate stimulates non-Ca(2+)-mediated and primes Ca(2+)-mediated exocytosis of insulin by activation of protein kinase C

Por Efanov, Alexandre M., Zaitsev, Sergei V., Berggren, Per-Olof
Publicado em 1997

“...d-myo-inositol 1,2,3,4,5,6-hexakisphosphate (InsP(6)), formed via complex pathways of inositol...”
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10

Interaction of human apurinic endonuclease and DNA polymerase β in the base excision repair pathway

Interaction of human apurinic endonuclease and DNA polymerase β in the base excision repair pathway

Por Bennett, Richard A. O., Wilson, David M., Wong, Donny, Demple, Bruce
Publicado em 1997

“... base excision repair synthesis and also can excise deoxyribose 5-phosphate after AP endonuclease...”
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11

Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

Por Lyapina, Svetlana A., Correll, Craig C., Kipreos, Edward T., Deshaies, Raymond J.
Publicado em 1998

“... of an effort to identify components and substrates of a putative human SCF complex, we isolated hSKP1 in a two...”
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12

Interactions with multiple peptide ligands determine the fate of developing thymocytes

Interactions with multiple peptide ligands determine the fate of developing thymocytes

Por Williams, Owen, Tarazona, Raquel, Wack, Andreas, Harker, Nicola, Roderick, Kathleen, Kioussis, Dimitris
Publicado em 1998

“... now extended these experiments by demonstrating that the antagonist peptide can inhibit natural...”
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13

The role of zinc fingers in transcriptional activation by transcription factor IIIA.

The role of zinc fingers in transcriptional activation by transcription factor IIIA.

Por Del Rio, S, Setzer, D R
Publicado em 1993

“... of these mutant proteins exhibit large decreases in their binding affinity for 5S rRNA genes in binary complexes...”
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14

A yeast genetic system for selecting small molecule inhibitors of protein–protein interactions in nanodroplets

A yeast genetic system for selecting small molecule inhibitors of protein–protein interactions in nanodroplets

Por Huang, Jing, Schreiber, Stuart L.
Publicado em 1997

“... products, however, that illustrate the feasibility of this approach. Split-pool synthesis now provides a...”
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15

Intramolecular arsanilazotyrosine-248-Zn complex of carboxypeptidase A: a monitor of multiple conformational states in solution.

Intramolecular arsanilazotyrosine-248-Zn complex of carboxypeptidase A: a monitor of multiple conformational states in solution.

Por Harrison, L W, Auld, D S, Vallee, B L
Publicado em 1975

“... about 10(5) sec-1, pH dependent dissociation of the metal complex. Ey in equilibrium Ey' (II), is much...”
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16

Identification and distribution of three serologically undetected alleles of HLA-DR by oligonucleotide.DNA typing analysis.

Identification and distribution of three serologically undetected alleles of HLA-DR by oligonucleotide.DNA typing analysis.

Por Tiercy, J M, Gorski, J, Jeannet, M, Mach, B
Publicado em 1988

“... beta I and DR beta III, now assigned names HLA-DRIB and HLA-DR3B) are functional. We have shown...”
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17

Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c.

Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c.

Por Martin, L H, Calabi, F, Lefebvre, F A, Bilsland, C A, Milstein, C
Publicado em 1987

“..., that are characteristic of the cortical stage of thymocyte maturation. CD1a was originally named HTA1 or T6 and thought...”
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18

Evidence for interstrand quadruplex formation in the dimerization of human immunodeficiency virus 1 genomic RNA.

Evidence for interstrand quadruplex formation in the dimerization of human immunodeficiency virus 1 genomic RNA.

Por Sundquist, W I, Heaphy, S
Publicado em 1993

“...Retroviruses package two homologous single-stranded RNA genomes within a gag protein-RNA complex...”
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19

Relationship of Leffler (Brønsted) α values and protein folding Φ values to position of transition-state structures on reaction coordinates

Relationship of Leffler (Brønsted) α values and protein folding Φ values to position of transition-state structures on reaction coordinates

Por Fersht, Alan R.
Publicado em 2004

“...) (equilibrium free energy) for a series of structural variants. Protein folding is more complex than simple...”
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20

Crystal structure of 2,5-diketo-d-gluconic acid reductase A complexed with NADPH at 2.1-Å resolution

Crystal structure of 2,5-diketo-d-gluconic acid reductase A complexed with NADPH at 2.1-Å resolution

Por Khurana, Sumit, Powers, David B., Anderson, Stephen, Blaber, Michael
Publicado em 1998

“...) to 2-keto-l-gulonate. Thus the three-dimensional structure has now been solved for a prokaryotic...”
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