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Phosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusion
Yeast vacuole fusion requires 4 SNAREs, 2 SNARE chaperone systems (Sec17p/Sec18p/ATP and the HOPS complex), and 2 phosphoinositides, phosphatidylinositol 3-phosphate [PI(3)P] and phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)]. By reconstituting proteoliposomal fusion with purified components, w...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752541/ https://ncbi.nlm.nih.gov/pubmed/19805279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908694106 |
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