Interactions with multiple peptide ligands determine the fate of developing thymocytes

Thymocytes are positively or negatively selected depending on interactions between their T cell receptors (TCR) and peptides presented by major histocompatibility complex molecules. We have previously shown that apoptosis of thymocytes from an αβ TCR-transgenic mouse (F5), induced by antigenic pepti...

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Библиографические подробности
Главные авторы: Williams, Owen, Tarazona, Raquel, Wack, Andreas, Harker, Nicola, Roderick, Kathleen, Kioussis, Dimitris
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC20443/
https://ncbi.nlm.nih.gov/pubmed/9576948
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