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Interactions with multiple peptide ligands determine the fate of developing thymocytes

Thymocytes are positively or negatively selected depending on interactions between their T cell receptors (TCR) and peptides presented by major histocompatibility complex molecules. We have previously shown that apoptosis of thymocytes from an αβ TCR-transgenic mouse (F5), induced by antigenic pepti...

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Detalhes bibliográficos
Main Authors: Williams, Owen, Tarazona, Raquel, Wack, Andreas, Harker, Nicola, Roderick, Kathleen, Kioussis, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20443/
https://ncbi.nlm.nih.gov/pubmed/9576948
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