Resultados da pesquisa - (( i cpt camp a non ) OR ((( j dnan clamp _ new ) OR ( _ gst cost ((cada nino) OR (cada dia)) ))))

1

Control of the replication initiator DnaA by an anti-cooperativity factor

Por Merrikh, Houra, Grossman, Alan D.
Publicado em 2011

“... regulator of replication initiation in Bacillus subtilis, interacts with DnaA and DnaN, the sliding...”
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2

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DnaAcos Hyperinitiates by Circumventing Regulatory Pathways that Control the Frequency of Initiation in Escherichia coli

Por Felczak, Magdalena M., Kaguni, Jon M.
Publicado em 2009

“... that dnaAcos is unresponsive to hda and dnaN, which encodes the β clamp, and also datA, a locus proposed...”
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3

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Intracellular calcium and cyclic nucleotide levels modulate neurite guidance by microtopographical substrate features

Por Li, Shufeng, Tuft, Bradley, Xu, Linjing, Polacco, Marc, Clarke, Joseph C., Guymon, C. Allan, Hansen, Marlan R.
Publicado no J Biomed Mater Res A (2016)

“... of cpt-cAMP or 8-Br-cGMP. MAIN RESULTS: Elevation of [Ca(2+)](i) by treatment of cultures with elevated...”
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4

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Cyclic Adenosine Monophosphate-Mediated Enhancement of Vascular Endothelial Growth Factor Released by Differentiated Human Monocytic Cells: The Role of Protein Kinase A

Por El-Zohairy, S.N., Oriowo, M.A., Ezeamuzie, C.I.
Publicado no Med Princ Pract (2015)

“... selective PKA inhibitors, suggesting that PKA is the downstream effector of cAMP activity. 8-CPT-cAMP, a...”
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5

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Non-genomic actions of 17β-oestradiol in mouse pancreatic β-cells are mediated by a cGMP-dependent protein kinase

Por Ropero, Ana B, Fuentes, Esther, Rovira, Juan M, Ripoll, Cristina, Soria, Bernat, Nadal, Angel
Publicado em 1999

“...1. Intracellular calcium concentration ([Ca(2+)](i)) was measured in mouse whole islets...”
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6

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NO donors potentiate the β-adrenergic stimulation of I(Ca,L) and the muscarinic activation of I(K,ACh) in rat cardiac myocytes

Por Abi-Gerges, Najah, Szabo, Gabor, Otero, Angela S, Fischmeister, Rodolphe, Méry, Pierre-François
Publicado em 2002

“...-tetramethylimidazoline-1-oxyl-3-oxide (100 μm), a NO trap. 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxaline-1-one (10 μm), a...”
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7

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Enhanced Rap1 Activation and Insulin Secretagogue Properties of an Acetoxymethyl Ester of an Epac-selective Cyclic AMP Analog in Rat INS-1 Cells: STUDIES WITH 8-pCPT-2′-O-Me-cAMP-AM

Por Chepurny, Oleg G., Leech, Colin A., Kelley, Grant G., Dzhura, Igor, Dzhura, Elvira, Li, Xiangquan, Rindler, Michael J., Schwede, Frank, Genieser, Hans G., Holz, George G.
Publicado em 2009

“... of the non-AM-ester of 8-pCPT-2′-O-Me-cAMP failed to stimulate insulin secretion and was a weak activator...”
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8

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Metabolites of an Epac-Selective cAMP Analog Induce Cortisol Synthesis by Adrenocortical Cells through a cAMP-Independent Pathway

Por Enyeart, Judith A., Enyeart, John J.
Publicado em 2009

“... that activated Rap1, a downstream effector of Epac2. Accordingly, putative metabolites of 8CPT-2′-OMe-cAMP...”
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9

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Evidence that the anti-spasmogenic effect of the β-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase

Por Spicuzza, Lucia, Belvisi, Maria G, Birrell, Mark A, Barnes, Peter J, Hele, David J, Giembycz, Mark A
Publicado em 2001

“... peptide (VIP) (1 μM) and the non-selective activator of PKA, Sp-8-CPT-cAMPS (10 μM), produced a non...”
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10

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Depolarization counteracts glucocorticoid inhibition of adenohypophysical corticotroph cells

Por Lim, M C, Shipston, M J, Antoni, F A
Publicado em 1998

“... showed that ACTH secretion stimulated by 1 mM CPT-cAMP was suppressed to 34±1.5% (n=12) of the control...”
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11

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Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis.

Por Jiang, C, Finkbeiner, W E, Widdicombe, J H, Miller, S S
Publicado em 1997

“... (DIDS), a blocker of Ca(2+)-activated Cl- channels, suggested that fluid secretion induced by CPT-cAMP...”
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12

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Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.

Por Lars Herfindal, Camilla Krakstad, Lene Myhren, Hanne Hagland, Reidun Kopperud, Knut Teigen, Frank Schwede, Rune Kleppe, Stein Ove Døskeland
Publicado em 2014-01-01

“...PLoS ONE...”
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13

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Introduction of Aromatic Ring-Containing Substituents in Cyclic Nucleotides Is Associated with Inhibition of Toxin Uptake by the Hepatocyte Transporters OATP 1B1 and 1B3

Por Herfindal, Lars, Krakstad, Camilla, Myhren, Lene, Hagland, Hanne, Kopperud, Reidun, Teigen, Knut, Schwede, Frank, Kleppe, Rune, Døskeland, Stein Ove
Publicado em 2014

“... and OATP1B3, unrelated to actions on Epac, PKA or PKG. Several cAMP analogs, particularly with 8-pCPT...”
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14

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Gene Expression Signatures of cAMP/Protein Kinase A (PKA)-promoted, Mitochondrial-dependent...

Por Zhang, Lingzhi, Zambon, Alexander C., Vranizan, Karen, Pothula, Kanishka, Conklin, Bruce R., Insel, Paul A.
Publicado em 2007

“... Affymetrix 430 2.0 arrays) revealed that WT and D(−) cells incubated with 8-CPT-cAMP have similar, but non...”
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15

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Epac–protein kinase C alpha signaling in purinergic P2X3R-mediated hyperalgesia after inflammation

Por Gu, Yanping, Li, Guangwen, Chen, Yong, Huang, Li-Yen Mae
Publicado no Pain (2016)

“... (cAMP)–dependent guanine nucleotide exchange factor 1 (Epac1) in rat sensory dorsal root ganglia (DRGs...”
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16

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A role for Piezo2 in EPAC1-dependent mechanical allodynia

Por Eijkelkamp, N, Linley, J.E., Torres, J.M., Bee, L., Dickenson, A.H., Gringhuis, M., Minett, M.S., Hong, G.S., Lee, E., Oh, U., Ishikawa, Y., Zwartkuis, F.J., Cox, J.J., Wood, J.N.
Publicado em 2013

“... allodynia is reduced in Epac1−/− mice. The Epac-selective cAMP analogue 8-pCPT sensitizes mechanically...”
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17

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Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides

Por Werner, Katharina, Schwede, Frank, Genieser, Hans-Gottfried, Geiger, Jörg, Butt, Elke
Publicado em 2011

“... low degree competition with the antibodies; however, with Rp-cAMPS, 8-Br-cGMP and 8-pCPT-cGMP, a...”
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18

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Acid Sensing Ion Channels (ASICs) in NS20Y cells – potential role in neuronal differentiation

Por O’Bryant, Zaven, Leng, Tiandong, Liu, Mingli, Inoue, Koichi, Vann, Kiara T., Xiong, Zhi-gang
Publicado no Mol Brain (2016)

“... with ASIC1a inhibition, ASIC1a knockdown with small interference RNA significantly attenuates cpt-cAMP...”
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19

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8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation

Por Liu, Qinlong, Rehman, Hasibur, Krishnasamy, Yasodha, Lemasters, John J, Zhong, Zhi
Publicado no Int J Physiol Pathophysiol Pharmacol (2017)

“..., a downstream signaling molecule of mTOR, was increased in LPG but suppressed in FPG. 8-pCPT-cGMP...”
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20

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Linkage of β(1)-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca(2+)/calmodulin kinase II

Por Zhu, Wei-Zhong, Wang, Shi-Qiang, Chakir, Khalid, Yang, Dongmei, Zhang, Tong, Brown, Joan Heller, Devic, Eric, Kobilka, Brian K., Cheng, Heping, Xiao, Rui-Ping
Publicado em 2003

“...β(1)-adrenergic receptor (β(1)AR) stimulation activates the classic cAMP/protein kinase A (PKA...”
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