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8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation
Permeant cGMP analogs prevent the mitochondria permeability transition (MPT) in vitro. In this study, we explored whether 8-pCPT-cGMP prevents the MPT and decreases post-transplant damage to fatty partial liver grafts (FPG) in vivo. Rats were fed a control or high-fat, high-fructose diet for 2-week....
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| Publicado en: | Int J Physiol Pathophysiol Pharmacol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
e-Century Publishing Corporation
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5498880/ https://ncbi.nlm.nih.gov/pubmed/28694919 |
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