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8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation

Permeant cGMP analogs prevent the mitochondria permeability transition (MPT) in vitro. In this study, we explored whether 8-pCPT-cGMP prevents the MPT and decreases post-transplant damage to fatty partial liver grafts (FPG) in vivo. Rats were fed a control or high-fat, high-fructose diet for 2-week....

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Podrobná bibliografie
Vydáno v:Int J Physiol Pathophysiol Pharmacol
Hlavní autoři: Liu, Qinlong, Rehman, Hasibur, Krishnasamy, Yasodha, Lemasters, John J, Zhong, Zhi
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498880/
https://ncbi.nlm.nih.gov/pubmed/28694919
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