Timosaponin B-II ameliorates diabetic nephropathy via TXNIP, mTOR, and NF-κB signaling pathways in alloxan-induced mice

Por Yuan, Yong-Liang, Guo, Chang-Run, Cui, Ling-Ling, Ruan, Shi-Xia, Zhang, Chun-Feng, Ji, De, Yang, Zhong-Lin, Li, Fei
Publicado no Drug Des Devel Ther (2015)

Past and current perspective on new therapeutic targets for Type-II diabetes

Por Patil PD, Mahajan UB, Patil KR, Chaudhari S, Patil CR, Agrawal YO, Ojha S, Goyal SN
Publicado em 2017-05-01

Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug Treatment

Por Hoffman-Luca, C. Gianna, Yang, Chao-Yie, Lu, Jianfeng, Ziazadeh, Daniel, McEachern, Donna, Debussche, Laurent, Wang, Shaomeng
Publicado no PLoS One (2015)

Otitis media induced by peptidoglycan-polysaccharide (PGPS) in TLR2-deficient (Tlr2(−/−)) mice for developing drug therapy

Por Zhang, Xiaolin, Zheng, Tihua, Sang, Lu, Apisa, Luke, Zhao, Hongchun, Fu, Fenghua, Wang, Qingzhu, Wang, Yanfei, Zheng, Qing Yin
Publicado no Infect Genet Evol (2015)

Using Patient-Specific Induced Pluripotent Stem Cells and Wild-Type Mice to Develop a Gene...

Por Wiley, Luke A., Burnight, Erin R., Drack, Arlene V., Banach, Bailey B., Ochoa, Dalyz, Cranston, Cathryn M., Madumba, Robert A., East, Jade S., Mullins, Robert F., Stone, Edwin M., Tucker, Budd A.
Publicado no Hum Gene Ther (2016)

Genotypic Changes in Human Immunodeficiency Virus Type 1 Associated with Loss of Suppression...

Por Eastman, P. Scott, Mittler, John, Kelso, Reed, Gee, Chris, Boyer, Eric, Kolberg, Janice, Urdea, Mickey, Leonard, John M., Norbeck, Daniel W., Mo, Hongmei, Markowitz, Martin
Publicado em 1998

MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL

Por Vikström, Ingela B, Slomp, Anne, Carrington, Emma M, Moesbergen, Laura M, Chang, Catherine, Kelly, Gemma L, Glaser, Stefan P, Jansen, J H Marco, Leusen, Jeanette H W, Strasser, Andreas, Huang, David C S, Lew, Andrew M, Peperzak, Victor, Tarlinton, David M
Publicado no Cell Death Dis (2016)

Hearing loss in children with HIV/AIDS

Por Ana Karina Lima Buriti, Simone Helena dos Santos Oliveira, Lilian Ferreira Muniz
Publicado em 2013-12-01

Prospective study on nanoparticle albumin-bound paclitaxel in advanced breast cancer: clinical results and biological observations in taxane-pretreated patients

Por Fabi, Alessandra, Giannarelli, Diana, Malaguti, Paola, Ferretti, Gianluigi, Vari, Sabrina, Papaldo, Paola, Nisticò, Cecilia, Caterino, Mauro, De Vita, Roy, Mottolese, Marcella, Iacorossi, Laura, Cognetti, Francesco
Publicado no Drug Des Devel Ther (2015)

Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma

Por De Sanctis, Rita, Marrari, Andrea, Marchetti, Silvia, Mussi, Chiara, Balzarini, Luca, Lutman, Fabio Romano, Daolio, Primo, Bastoni, Stefano, Bertuzzi, Alexia Francesca, Quagliuolo, Vittorio, Santoro, Armando
Publicado no Drug Des Devel Ther (2015)

Nanostructured lipid carriers for incorporation of copper(II) complexes to be used against Mycobacterium tuberculosis

Por Sato, Mariana R, Oshiro Junior, João A, Machado, Rachel TA, de Souza, Paula C, Campos, Débora L, Pavan, Fernando R, da Silva, Patricia B, Chorilli, Marlus
Publicado no Drug Des Devel Ther (2017)

High-Normal Serum Uric Acid Increases Risk of Early Progressive Renal Function Loss in Type 1 Diabetes: Results of a 6-year follow-up

Por Ficociello, Linda H., Rosolowsky, Elizabeth T., Niewczas, Monika A., Maselli, Nicholas J., Weinberg, Janice M., Aschengrau, Ann, Eckfeldt, John H., Stanton, Robert C., Galecki, Andrzej T., Doria, Alessandro, Warram, James H., Krolewski, Andrzej S.
Publicado em 2010

Beta-Cell Preservation…Is Weight Loss the Answer?

Por Mazza, Angela D., Pratley, Richard E., Smith, Steven R.
Publicado em 2011

Fondaparinux vs warfarin for the treatment of unsuspected pulmonary embolism in cancer patients

Por Amato, Bruno, Compagna, Rita, Rocca, Aldo, Bianco, Tommaso, Milone, Marco, Sivero, Luigi, Vigliotti, Gabriele, Amato, Maurizio, Danzi, Michele, Aprea, Giovanni, Gallelli, Luca, de Franciscis, Stefano, Serra, Raffaele
Publicado no Drug Des Devel Ther (2016)

Development of Resistance in Wild-Type and Hypermutable Pseudomonas aeruginosa Strains Exposed...

Por Henrichfreise, Beate, Wiegand, Irith, Luhmer-Becker, Ingeborg, Wiedemann, Bernd
Publicado em 2007

The Complement Regulatory Protein CD46 Deficient Mouse Spontaneously Develops Dry-Type Age-Related Macular Degeneration–Like Phenotype

Por Lyzogubov, Valeriy V., Bora, Puran S., Wu, Xiaobo, Horn, Leah E., de Roque, Ryan, Rudolf, Xeniya V., Atkinson, John P., Bora, Nalini S.
Publicado no Am J Pathol (2016)

Resistance of Human Immunodeficiency Virus Type 1 to a Third-Generation Fusion Inhibitor Requires...

Por Eggink, Dirk, Bontjer, Ilja, Langedijk, Johannes P. M., Berkhout, Ben, Sanders, Rogier W.
Publicado em 2011

The impact of weight loss among seniors on Medicare spending

Por Thorpe, Kenneth E, Yang, Zhou, Long, Kathleen M, Garvey, W Timothy
Publicado em 2013

Lifestyle and Pharmacological Approaches to Weight Loss: Efficacy and Safety

Por Bray, George A.
Publicado em 2008

Genetic and pharmacological intervention for treatment/prevention of hearing loss

Por Cotanche, Douglas A.
Publicado em 2008