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1
Por Christopher S. Koivisto, Melodie Parrish, Santosh B. Bonala, Soo Ngoi, Adrian Torres, James Gallagher, Rebekah Sanchez-Hodge, Victor Zeinner, Georges J. Nahhas, Bei Liu, David E. Cohn, Floor J. Backes, Paul J. Goodfellow, Helen M. Chamberlin, Gustavo Leone
Publicado em 2020-10-01
Assuntos:
“...Preclinical drug evaluation...”Publicado em 2020-10-01
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2
Por Kraniak, Janice M., Chalasani, Anita, Wallace, Margaret R., Mattingly, Raymond R.
Publicado no Exp Neurol (2017)
“..., an inhibitor of MAP kinase kinase (MEK). We have developed three-dimensional (3D) cell culture models...”Publicado no Exp Neurol (2017)
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3
“...Neurofibromatosis Type 1 (NF1) is a common genetic disorder and cancer predisposition syndrome (1...”
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4
Por Cammalleri, Maurizio, Dal Monte, Massimo, Locri, Filippo, Pecci, Valeria, De Rosa, Mario, Pavone, Vincenzo, Bagnoli, Paola
Publicado no J Cell Mol Med (2019)
“...Retinitis pigmentosa (RP) is characterized by progressive loss of vision due to photoreceptor...”Publicado no J Cell Mol Med (2019)
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5
Por Lyzogubov, Valeriy V., Bora, Puran S., Wu, Xiaobo, Horn, Leah E., de Roque, Ryan, Rudolf, Xeniya V., Atkinson, John P., Bora, Nalini S.
Publicado no Am J Pathol (2016)
“... should provide valuable insights into pathogenesis and a test model system for novel drug targets. More...”Publicado no Am J Pathol (2016)
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6
Por Roesti, Elisa S., Boyle, Christina N., Zeman, Daniel T., Sande-Melon, Marcos, Storni, Federico, Cabral-Miranda, Gustavo, Knuth, Alexander, Lutz, Thomas A., Vogel, Monique, Bachmann, Martin F.
Publicado no Vaccines (Basel) (2020)
“...Type 2 diabetes mellitus (T2DM) is a chronic progressive disease characterized by insulin...”Publicado no Vaccines (Basel) (2020)
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7
Por Elisa S. Roesti, Christina N. Boyle, Daniel T. Zeman, Marcos Sande-Melon, Federico Storni, Gustavo Cabral-Miranda, Alexander Knuth, Thomas A. Lutz, Monique Vogel, Martin F. Bachmann
Publicado em 2020-03-01
“...Type 2 diabetes mellitus (T2DM) is a chronic progressive disease characterized by insulin...”Publicado em 2020-03-01
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8
Por Liu, Jin, Bradley, Ryan, Eckmann, David M., Ayyaswamy, Portonovo S., Radhakrishnan, Ravi
Publicado em 2011
“... and diagnostic applications. In this paper we review the recent development of models at multiple length and time...”Publicado em 2011
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9
Por Anichtchik, Oleg, Diekmann, Heike, Fleming, Angeleen, Roach, Alan, Goldsmith, Paul, Rubinsztein, David C.
Publicado no J Neurosci (2008)
“... of the disease. Although the mutations appear to result in a loss of function, the roles of this protein...”Publicado no J Neurosci (2008)
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10
Por Bussière, Françoise I., Niepceron, Alisson, Sausset, Alix, Esnault, Evelyne, Silvestre, Anne, Walker, Robert A., Smith, Nicholas C., Quéré, Pascale, Laurent, Fabrice
Publicado no Parasit Vectors (2018)
“... mixed cell populations; no cell line model has been able to consistently support the development...”Publicado no Parasit Vectors (2018)
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11
Por Zhang, Xiaolin, Zheng, Tihua, Sang, Lu, Apisa, Luke, Zhao, Hongchun, Fu, Fenghua, Wang, Qingzhu, Wang, Yanfei, Zheng, Qing Yin
Publicado no Infect Genet Evol (2015)
“... animal model. Peptidoglycan-polysaccharide (PGPS) of the bacterial cell wall can induce inflammation...”Publicado no Infect Genet Evol (2015)
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12
Por Hoffman-Luca, C. Gianna, Yang, Chao-Yie, Lu, Jianfeng, Ziazadeh, Daniel, McEachern, Donna, Debussche, Laurent, Wang, Shaomeng
Publicado no PLoS One (2015)
“.... Computational modeling suggested that a p53 tetramer containing two wild-type p53 molecules and two C176F...”Publicado no PLoS One (2015)
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13
Por Papathanasiou, Theodoros, Strathe, Anders, Agersø, Henrik, Lund, Trine Meldgaard, Overgaard, Rune Viig
Publicado no Diabetes Obes Metab (2020)
“... after treatment cessation at week 56 (data not included in model development). RESULTS: A...”Publicado no Diabetes Obes Metab (2020)
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14
Por De Rose, Francescaelena, Marotta, Roberto, Poddighe, Simone, Talani, Giuseppe, Catelani, Tiziano, Setzu, Maria Dolores, Solla, Paolo, Marrosu, Francesco, Sanna, Enrico, Kasture, Sanjay, Acquas, Elio, Liscia, Anna
Publicado no PLoS One (2016)
“... methanolic extract (Wse) on the LRRK2 loss-of-function Dm model of PD. To this end mutant and wild type (WT...”Publicado no PLoS One (2016)
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15
Por Dhaher, Roni, Damisah, Eyiyemisi C, Wang, Helen, Gruenbaum, Shaun, Ong, Caroline, Zaveri, Hitten P, Gruenbaum, Benjamin, Eid, Tore
Publicado em 2014
“... of the most severe type of seizures in the MSO model of MTLE. These results may have implications...”Publicado em 2014
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16
Por Henrichfreise, Beate, Wiegand, Irith, Luhmer-Becker, Ingeborg, Wiedemann, Bernd
Publicado em 2007
“... and the development of mutation-mediated resistance in wild-type and hypermutable Pseudomonas aeruginosa strains. We...”Publicado em 2007
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17
Por McClean, Paula L., Parthsarathy, Vadivel, Faivre, Emilie, Hölscher, Christian
Publicado no J Neurosci (2011)
“...Type 2 diabetes is a risk factor for Alzheimer's disease, most likely linked to an impairment...”Publicado no J Neurosci (2011)
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18
Por Spagnuolo, Vincenzo, Galli, Laura, Poli, Andrea, Salpietro, Stefania, Gianotti, Nicola, Piatti, Piermarco, Cossarini, Francesca, Vinci, Concetta, Carini, Elisabetta, Lazzarin, Adriano, Castagna, Antonella
Publicado no BMC Infect Dis (2017)
“... investigated the associations of statin use and exposure to antiretroviral drugs with type 2 DM onset in a...”Publicado no BMC Infect Dis (2017)
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19
Por Kobet, Robert A., Pan, Xiaoping, Zhang, Baohong, Pak, Stephen C., Asch, Adam S., Lee, Myon-Hee
Publicado em 2014
“... provides an exceptional model for genetic, molecular, and cellular analysis of human disease-related genes...”Publicado em 2014
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20
IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis
Por Gao, Ya, de Wit, Maurice, Struys, Eduard A., van der Linde, Herma C. Z., Salomons, Gajja S., Lamfers, Martine L. M., Willemsen, Rob, Sillevis Smitt, Peter A. E., French, Pim J.
Publicado no PLoS One (2018)
“... in IDH1 that can be used for functional analysis and drug screening. Our model systems help understand...”Publicado no PLoS One (2018)
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