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2
Endosomal generation of cAMP in GPCR signaling
“.... In the new model, GPCRs mediate G-protein signaling not only from the plasma membrane but also from endosomal...”
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Regulation of Nuclear PKA revealed by spatiotemporal manipulation of cAMP
“... manipulation of cAMP in these compartments. Here we characterize a new method using bicarbonate-activatable...”
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8
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia
Por Law, Philip J., Berndt, Sonja I., Speedy, Helen E., Camp, Nicola J., Sava, Georgina P., Skibola, Christine F., Holroyd, Amy, Joseph, Vijai, Sunter, Nicola J., Nieters, Alexandra, Bea, Silvia, Monnereau, Alain, Martin-Garcia, David, Goldin, Lynn R., Clot, Guillem, Teras, Lauren R., Quintela, Inés, Birmann, Brenda M., Jayne, Sandrine, Cozen, Wendy, Majid, Aneela, Smedby, Karin E., Lan, Qing, Dearden, Claire, Brooks-Wilson, Angela R., Hall, Andrew G., Purdue, Mark P., Mainou-Fowler, Tryfonia, Vajdic, Claire M., Jackson, Graham H., Cocco, Pierluigi, Marr, Helen, Zhang, Yawei, Zheng, Tongzhang, Giles, Graham G., Lawrence, Charles, Call, Timothy G., Liebow, Mark, Melbye, Mads, Glimelius, Bengt, Mansouri, Larry, Glenn, Martha, Curtin, Karen, Diver, W Ryan, Link, Brian K., Conde, Lucia, Bracci, Paige M., Holly, Elizabeth A., Jackson, Rebecca D., Tinker, Lesley F., Benavente, Yolanda, Boffetta, Paolo, Brennan, Paul, Maynadie, Marc, McKay, James, Albanes, Demetrius, Weinstein, Stephanie, Wang, Zhaoming, Caporaso, Neil E., Morton, Lindsay M., Severson, Richard K., Riboli, Elio, Vineis, Paolo, Vermeulen, Roel C. H., Southey, Melissa C., Milne, Roger L., Clavel, Jacqueline, Topka, Sabine, Spinelli, John J., Kraft, Peter, Ennas, Maria Grazia, Summerfield, Geoffrey, Ferri, Giovanni M., Harris, Robert J., Miligi, Lucia, Pettitt, Andrew R., North, Kari E., Allsup, David J., Fraumeni, Joseph F., Bailey, James R., Offit, Kenneth, Pratt, Guy, Hjalgrim, Henrik, Pepper, Chris, Chanock, Stephen J., Fegan, Chris, Rosenquist, Richard, de Sanjose, Silvia, Carracedo, Angel, Dyer, Martin J. S., Catovsky, Daniel, Campo, Elias, Cerhan, James R., Allan, James M., Rothman, Nathanial, Houlston, Richard, Slager, Susan
Publicado no Nat Commun (2017)
“...)). These new and established risk loci map to areas of active chromatin and show an over-representation...”
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9
Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia
Por Berndt, Sonja I., Camp, Nicola J., Skibola, Christine F., Vijai, Joseph, Wang, Zhaoming, Gu, Jian, Nieters, Alexandra, Kelly, Rachel S., Smedby, Karin E., Monnereau, Alain, Cozen, Wendy, Cox, Angela, Wang, Sophia S., Lan, Qing, Teras, Lauren R., Machado, Moara, Yeager, Meredith, Brooks-Wilson, Angela R., Hartge, Patricia, Purdue, Mark P., Birmann, Brenda M., Vajdic, Claire M., Cocco, Pierluigi, Zhang, Yawei, Giles, Graham G., Zeleniuch-Jacquotte, Anne, Lawrence, Charles, Montalvan, Rebecca, Burdett, Laurie, Hutchinson, Amy, Ye, Yuanqing, Call, Timothy G., Shanafelt, Tait D., Novak, Anne J., Kay, Neil E., Liebow, Mark, Cunningham, Julie M., Allmer, Cristine, Hjalgrim, Henrik, Adami, Hans-Olov, Melbye, Mads, Glimelius, Bengt, Chang, Ellen T., Glenn, Martha, Curtin, Karen, Cannon-Albright, Lisa A., Diver, W Ryan, Link, Brian K., Weiner, George J., Conde, Lucia, Bracci, Paige M., Riby, Jacques, Arnett, Donna K., Zhi, Degui, Leach, Justin M., Holly, Elizabeth A., Jackson, Rebecca D., Tinker, Lesley F., Benavente, Yolanda, Sala, Núria, Casabonne, Delphine, Becker, Nikolaus, Boffetta, Paolo, Brennan, Paul, Foretova, Lenka, Maynadie, Marc, McKay, James, Staines, Anthony, Chaffee, Kari G., Achenbach, Sara J., Vachon, Celine M., Goldin, Lynn R., Strom, Sara S., Leis, Jose F., Weinberg, J. Brice, Caporaso, Neil E., Norman, Aaron D., De Roos, Anneclaire J., Morton, Lindsay M., Severson, Richard K., Riboli, Elio, Vineis, Paolo, Kaaks, Rudolph, Masala, Giovanna, Weiderpass, Elisabete, Chirlaque, María- Dolores, Vermeulen, Roel C. H., Travis, Ruth C., Southey, Melissa C., Milne, Roger L., Albanes, Demetrius, Virtamo, Jarmo, Weinstein, Stephanie, Clavel, Jacqueline, Zheng, Tongzhang, Holford, Theodore R., Villano, Danylo J., Maria, Ann, Spinelli, John J., Gascoyne, Randy D., Connors, Joseph M., Bertrand, Kimberly A., Giovannucci, Edward, Kraft, Peter, Kricker, Anne, Turner, Jenny, Ennas, Maria Grazia, Ferri, Giovanni M., Miligi, Lucia, Liang, Liming, Ma, Baoshan, Huang, Jinyan, Crouch, Simon, Park, Ju-Hyun, Chatterjee, Nilanjan, North, Kari E., Snowden, John A., Wright, Josh, Fraumeni, Joseph F., Offit, Kenneth, Wu, Xifeng, de Sanjose, Silvia, Cerhan, James R., Chanock, Stephen J., Rothman, Nathaniel, Slager, Susan L.
Publicado no Nat Commun (2016)
“... controls with follow-up replication in 1,958 cases and 5,530 controls. Here we report three new loci at 3p...”
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10
Retromer arrests receptor on the run
Por van Weering, Jan RT, Cullen, Peter J
Publicado em 2011
“... complex with its receptor and prolongs cAMP production even after internalization and recruitment...”
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12
Hormone-dependent expression of a steroidogenic acute regulatory protein natural antisense transcript in MA-10 mouse tumor Leydig cells.
“... chorionic gonadotropin stimulates Star NAT expression via cAMP. Our results show that sense-antisense Star...”
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17
The TOTAL RECALL™ Program: A Relational Office Database Interfacable with Briefcase Computers
“..., and Billing. The HX-20 can retrieve from tape and display clinical data on any patient, and allow input of new...”
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18
Good enough practices in scientific computing
“...Computers are now essential in all branches of science, but most researchers are never taught...”
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Information technology and lawyers advanced technology in the legal domain, from challenges to daily routine /
Por Lodder, Arno R., Oskamp, Anja.
Publicado em 2006
“... and academics, and can serve in any (post)graduate courses on computer science, law, business, etc. The editors...”
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