Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk

Por Calandra, Sebastiano, Tarugi, Patrizia, Speedy, Helen E., Dean, Andrew F., Bertolini, Stefano, Shoulders, Carol C.
Publicado em 2011

Germ line mutations in shelterin complex genes are associated with familial chronic lymphocytic leukemia

Por Speedy, Helen E., Kinnersley, Ben, Chubb, Daniel, Broderick, Peter, Law, Philip J., Litchfield, Kevin, Jayne, Sandrine, Dyer, Martin J. S., Dearden, Claire, Follows, George A., Catovsky, Daniel, Houlston, Richard S.
Publicado no Blood (2016)

The origin, global distribution, and functional impact of the human 8p23 inversion polymorphism

Por Salm, Maximilian P.A., Horswell, Stuart D., Hutchison, Claire E., Speedy, Helen E., Yang, Xia, Liang, Liming, Schadt, Eric E., Cookson, William O., Wierzbicki, Anthony S., Naoumova, Rossi P., Shoulders, Carol C.
Publicado em 2012

Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci

Por Jäger, Roland, Migliorini, Gabriele, Henrion, Marc, Kandaswamy, Radhika, Speedy, Helen E., Heindl, Andreas, Whiffin, Nicola, Carnicer, Maria J., Broome, Laura, Dryden, Nicola, Nagano, Takashi, Schoenfelder, Stefan, Enge, Martin, Yuan, Yinyin, Taipale, Jussi, Fraser, Peter, Fletcher, Olivia, Houlston, Richard S.
Publicado no Nat Commun (2015)

Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition

Por Aikio, Mari, Elamaa, Harri, Vicente, David, Izzi, Valerio, Kaur, Inderjeet, Seppinen, Lotta, Speedy, Helen E., Kaminska, Dorota, Kuusisto, Sanna, Sormunen, Raija, Heljasvaara, Ritva, Jones, Emma L., Muilu, Mikko, Jauhiainen, Matti, Pihlajamäki, Jussi, Savolainen, Markku J., Shoulders, Carol C., Pihlajaniemi, Taina
Publicado em 2014

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism

Por Kandaswamy, Radhika, Sava, Georgina P., Speedy, Helen E., Beà, Sílvia, Martín-Subero, José I., Studd, James B., Migliorini, Gabriele, Law, Philip J., Puente, Xose S., Martín-García, David, Salaverria, Itziar, Gutiérrez-Abril, Jesús, López-Otín, Carlos, Catovsky, Daniel, Allan, James M., Campo, Elías, Houlston, Richard S.
Publicado no Cell Rep (2016)

CDKN2B expression in adipose tissue of familial combined hyperlipidemia patients

Por Horswell, Stuart D., Fryer, Lee G. D., Hutchison, Claire E., Zindrou, Dlear, Speedy, Helen E., Town, Margaret-M., Duncan, Emma J., Sivapackianathan, Rasheeta, Patel, Hetal N., Jones, Emma L., Braithwaite, Adam, Salm, Max P. A., Neuwirth, Claire K. Y., Potter, Elizabeth, Anderson, Jonathan R., Taylor, Kenneth M., Seed, Mary, Betteridge, D. John, Crook, Martin A., Wierzbicki, Anthony S., Scott, James, Naoumova, Rossi P., Shoulders, Carol C.
Publicado em 2013

Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci

Por Law, Philip J., Sud, Amit, Mitchell, Jonathan S., Henrion, Marc, Orlando, Giulia, Lenive, Oleg, Broderick, Peter, Speedy, Helen E., Johnson, David C., Kaiser, Martin, Weinhold, Niels, Cooke, Rosie, Sunter, Nicola J., Jackson, Graham H., Summerfield, Geoffrey, Harris, Robert J., Pettitt, Andrew R., Allsup, David J., Carmichael, Jonathan, Bailey, James R., Pratt, Guy, Rahman, Thahira, Pepper, Chris, Fegan, Chris, von Strandmann, Elke Pogge, Engert, Andreas, Försti, Asta, Chen, Bowang, Filho, Miguel Inacio da Silva, Thomsen, Hauke, Hoffmann, Per, Noethen, Markus M., Eisele, Lewin, Jöckel, Karl-Heinz, Allan, James M., Swerdlow, Anthony J., Goldschmidt, Hartmut, Catovsky, Daniel, Morgan, Gareth J., Hemminki, Kari, Houlston, Richard S.
Publicado no Sci Rep (2017)

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

Por Law, Philip J., Berndt, Sonja I., Speedy, Helen E., Camp, Nicola J., Sava, Georgina P., Skibola, Christine F., Holroyd, Amy, Joseph, Vijai, Sunter, Nicola J., Nieters, Alexandra, Bea, Silvia, Monnereau, Alain, Martin-Garcia, David, Goldin, Lynn R., Clot, Guillem, Teras, Lauren R., Quintela, Inés, Birmann, Brenda M., Jayne, Sandrine, Cozen, Wendy, Majid, Aneela, Smedby, Karin E., Lan, Qing, Dearden, Claire, Brooks-Wilson, Angela R., Hall, Andrew G., Purdue, Mark P., Mainou-Fowler, Tryfonia, Vajdic, Claire M., Jackson, Graham H., Cocco, Pierluigi, Marr, Helen, Zhang, Yawei, Zheng, Tongzhang, Giles, Graham G., Lawrence, Charles, Call, Timothy G., Liebow, Mark, Melbye, Mads, Glimelius, Bengt, Mansouri, Larry, Glenn, Martha, Curtin, Karen, Diver, W Ryan, Link, Brian K., Conde, Lucia, Bracci, Paige M., Holly, Elizabeth A., Jackson, Rebecca D., Tinker, Lesley F., Benavente, Yolanda, Boffetta, Paolo, Brennan, Paul, Maynadie, Marc, McKay, James, Albanes, Demetrius, Weinstein, Stephanie, Wang, Zhaoming, Caporaso, Neil E., Morton, Lindsay M., Severson, Richard K., Riboli, Elio, Vineis, Paolo, Vermeulen, Roel C. H., Southey, Melissa C., Milne, Roger L., Clavel, Jacqueline, Topka, Sabine, Spinelli, John J., Kraft, Peter, Ennas, Maria Grazia, Summerfield, Geoffrey, Ferri, Giovanni M., Harris, Robert J., Miligi, Lucia, Pettitt, Andrew R., North, Kari E., Allsup, David J., Fraumeni, Joseph F., Bailey, James R., Offit, Kenneth, Pratt, Guy, Hjalgrim, Henrik, Pepper, Chris, Chanock, Stephen J., Fegan, Chris, Rosenquist, Richard, de Sanjose, Silvia, Carracedo, Angel, Dyer, Martin J. S., Catovsky, Daniel, Campo, Elias, Cerhan, James R., Allan, James M., Rothman, Nathanial, Houlston, Richard, Slager, Susan
Publicado no Nat Commun (2017)