A Genomic DNA Reporter Screen Identifies Squalene Synthase Inhibitors That Act Cooperatively with Statins to Upregulate the Low-Density Lipoprotein Receptor

著者: Kerr, Alastair G., Tam, Lawrence C. S., Hale, Ashley B., Cioroch, Milena, Douglas, Gillian, Agkatsev, Sarina, Hibbitt, Olivia, Mason, Joseph, Holt-Martyn, James, Bataille, Carole J. R., Wynne, Graham M., Channon, Keith M., Russell, Angela J., Wade-Martins, Richard
出版年 J Pharmacol Exp Ther (2017)

Design, development, drug-likeness, and molecular docking studies of novel piperidin-4-imine derivatives as antitubercular agents

著者: Revathi, Rajappan, Venkatesha Perumal, Ramachandran, Pai, Karkala Sreedhara Ranganath, Arunkumar, Govindakarnavar, Sriram, Dharmarajan, Kini, Suvarna Ganesh
出版年 Drug Des Devel Ther (2015)

Novel Strategies for Anterior Segment Ocular Drug Delivery

著者: Cholkar, Kishore, Patel, Sulabh P., Vadlapudi, Aswani Dutt, Mitra, Ashim K.
出版事項 2013

Recent Progress in the Development of New Antimalarial Drugs with Novel Targets

著者: Belete, Tafere Mulaw
出版年 Drug Des Devel Ther (2020)

THER-22. BROMODOMAIN INHIBITORS INDUCE DOWNREGULATION OF DNA DAMAGE REPAIR PATHWAYS AND OFFER NOVEL...

著者: Lam, Fred C, Vu-Han, Tu-Lan, Van de Kooj, Bert, Kong, Yi Wen, Bandopadhayay, Pratiti, Beroukhim, Rameen, Sarkaria, Jann, Hammond, Paula, Yaffe, Michael
出版年 Neuro Oncol (2019)

SYSTEMATIC EVALUATION OF DRUG-DISEASE RELATIONSHIPS TO IDENTIFY LEADS FOR NOVEL DRUG USES

著者: Chiang, Annie P., Butte, Atul J.
出版事項 2009

Novel drug targets based on metallobiology of Alzheimer’s disease

著者: Bandyopadhyay, Sanghamitra, Huang, Xudong, Lahiri, Debomoy K, Rogers, Jack T
出版年 Expert Opin Ther Targets (2010)

Microdose-induced Drug-DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice

著者: Zimmermann, Maike, Wang, Si-Si, Zhang, Hongyong, Lin, Tzu-yin, Malfatti, Michael, Haack, Kurt, Ognibene, Ted, Yang, Hongyuan, Airhart, Susan, Turteltaub, Kenneth W., Cimino, George D., Tepper, Clifford G., Drakaki, Alexandra, Chamie, Karim, de Vere White, Ralph, Pan, Chong-xian, Henderson, Paul T.
出版年 Mol Cancer Ther (2016)

Lifitegrast: a novel drug for patients with dry eye disease

著者: Haber, Stacy L., Benson, Vera, Buckway, Casey J., Gonzales, Jennifer M., Romanet, David, Scholes, Brittany
出版年 Ther Adv Ophthalmol (2019)

THER-03. IN VITRO EVALUATION OF THE EFFECT OF CANNABIDIOL ON PAEDIATRIC BRAIN TUMOUR CELL LINES USING A PULSED TREATMENT REGIME

著者: Faulkes, Sophie, Lockwood, George, O’Sullivan, Saoirse E, Grundy, Richard G, Storer, Lisa C D
出版年 Neuro Oncol (2020)

Novel drugs that target the estrogen-related receptor alpha: their therapeutic potential in breast cancer

著者: May FEB
出版事項 2014-05-01

Induction of glutathione-dependent DNA double-strand breaks by the novel anticancer drug brostallicin

著者: Guirouilh-Barbat, Josée, Zhang, Yong-Wei, Pommier, Yves
出版事項 2009

Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M(4) Muscarinic Receptor as a Novel Therapeutic Target

著者: Gogliotti, Rocco G., Fisher, Nicole M., Stansley, Branden J., Jones, Carrie K., Lindsley, Craig W., Conn, P. Jeffrey, Niswender, Colleen M.
出版年 J Pharmacol Exp Ther (2018)

A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction

著者: Hay, Meredith, Polt, Robin, Heien, Michael L., Vanderah, Todd W., Largent-Milnes, Tally M., Rodgers, Kathleen, Falk, Torsten, Bartlett, Mitchell J., Doyle, Kristian P., Konhilas, John P.
出版年 J Pharmacol Exp Ther (2019)

Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

著者: Singh, Akhand Pratap, Biswas, Arpan, Shukla, Aparna, Maiti, Pralay
出版年 Signal Transduct Target Ther (2019)

Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug–Drug Interactions

著者: Elens, Laure, Langman, Loralie J., Hesselink, Dennis A., Bergan, Stein, Moes, Dirk Jan A.R., Molinaro, Mariadelfina, Venkataramanan, Raman, Lemaitre, Florian
出版年 Ther Drug Monit (2020)

THER-28. A CK1α ACTIVATOR PENETRATES THE BRAIN, AND SHOWS EFFICACY AGAINST DRUG-RESISTANT METASTATIC MEDULLOBLASTOMA

著者: Rodriguez, Jezabel, Li, Bin, Long, Jun, Shen, Chen, Yang, Fan, Orthon, Darren, Collins, Sara, Kasahara, Noriyuki, Ayad, Nagi, McCrea, Heather, Roussel, Martine, Weiss, William, Capobianco, Anthony, Robbins, David
出版年 Neuro Oncol (2019)

Artificial intelligence-based computational framework for drug-target prioritization and inference of novel repositionable drugs for Alzheimer’s disease

著者: Tsuji, Shingo, Hase, Takeshi, Yachie-Kinoshita, Ayako, Nishino, Taiko, Ghosh, Samik, Kikuchi, Masataka, Shimokawa, Kazuro, Aburatani, Hiroyuki, Kitano, Hiroaki, Tanaka, Hiroshi
出版年 Alzheimers Res Ther (2021)

Novel antibody–drug conjugates for triple negative breast cancer

著者: Nagayama, Aiko, Vidula, Neelima, Ellisen, Leif, Bardia, Aditya
出版年 Ther Adv Med Oncol (2020)

Precision dosing to avoid adverse drug reactions

著者: Polasek, Thomas M., Kirkpatrick, Carl M. J., Rostami-Hodjegan, Amin
出版年 Ther Adv Drug Saf (2019)