Restoration of Rostral Ventrolateral Medulla Cystathionine-γ Lyase Activity Underlies Moxonidine-Evoked Neuroprotection and Sympathoinhibition in Diabetic Rats

Por Fouda, Mohamed A., El-Sayed, Shaimaa S., Abdel-Rahman, Abdel A.
Publicado no J Pharmacol Exp Ther (2018)

In Vitro Evaluation of Guanidine Analogs as Sigma Receptor Ligands for Potential Anti-Stroke Therapeutics

Por Behensky, Adam A., Cortes-Salva, Michelle, Seminerio, Michael J., Matsumoto, Rae R., Antilla, Jon C., Cuevas, Javier
Publicado em 2013

A Novel Factor Xa-Inhibiting Peptide from Centipedes Venom

Por Kong, Yi, Shao, Yu, Chen, Hao, Ming, Xin, Wang, Jin-Bin, Li, Zhi-Yu, Wei, Ji-Fu
Publicado em 2013

Discovery of Novel Inhibitors Targeting Multi-UDP-hexose Pyrophosphorylases as Anticancer Agents

Por Yang, Yueqin, Vankayalapati, Hariprasad, Tang, Manshu, Zheng, Yingbo, Li, Yingri, Ma, Cong, Lai, Kent
Publicado no Molecules (2020)

Impact of DPYD, DPYS, and UPB1 gene variations on severe drug‐related toxicity in patients with cancer

Por Yokoi, Katsuyuki, Nakajima, Yoko, Matsuoka, Hiroshi, Shinkai, Yasuko, Ishihara, Takuma, Maeda, Yasuhiro, Kato, Takema, Katsuno, Hidetoshi, Masumori, Koji, Kawada, Kenji, Yoshikawa, Tetsushi, Ito, Tetsuya, Kurahashi, Hiroki
Publicado no Cancer Sci (2020)

Tyrosine hydroxylase deficiency—Clinical insights and a novel deletion in TH gene in an Indian patient

Por Bijarnia‐Mahay, Sunita, Jain, Vivek, Thöny, Beat
Publicado no JIMD Rep (2020)

Tyrosine hydroxylase deficiency—Clinical insights and a novel deletion in TH gene in an Indian patient

Por Sunita Bijarnia‐Mahay, Vivek Jain, Beat Thöny
Publicado em 2020-05-01

Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation

Por Thornton, C C, Al-Rashed, F, Calay, D, Birdsey, G M, Bauer, A, Mylroie, H, Morley, B J, Randi, A M, Haskard, D O, Boyle, J J, Mason, J C
Publicado no Ann Rheum Dis (2016)

Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts

Por Cao, P, Maira, S-M, García-Echeverría, C, Hedley, D W
Publicado em 2009

A Cyclic Dodecapeptide–Multiple-Antigen Peptide Conjugate from the Undecapeptidyl Arch (from Arg(168) to Cys(178)) of Extracellular Loop 2 in CCR5 as a Novel Human Immunodeficiency Virus Type 1...

Por Misumi, Shogo, Nakajima, Reina, Takamune, Nobutoki, Shoji, Shozo
Publicado em 2001

Xyloketal B Attenuates Atherosclerotic Plaque Formation and Endothelial Dysfunction in Apolipoprotein E Deficient Mice

Por Li-Yan Zhao, Jie Li, Feng Yuan, Mei Li, Quan Zhang, Ji-Yan Pang, Bin Zhang, Fang-Yun Sun, Hong-Shuo Sun, Qian Li, Lu Cao, Yu Xie, Yong-Cheng Lin, Jie Liu, Hong-Mei Tan, Guan-Lei Wang, Yun-Ying Huang
Publicado em 2015-04-01

Metformin Disrupts Crosstalk Between G protein-Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth

Por Kisfalvi, Krisztina, Eibl, Guido, Sinnett-Smith, James, Rozengurt, Enrique
Publicado em 2009

A Role for Calmodulin-Stimulated Adenylyl Cyclases in Cocaine Sensitization

Por DiRocco, Derek P., Scheiner, Zachary S., Sindreu, Carlos Balet, Chan, Guy C.-K., Storm, Daniel R.
Publicado em 2009

GLYX-13 (rapastinel) ameliorates subchronic phencyclidine- and ketamine-induced declarative memory deficits in mice

Por Rajagopal, Lakshmi, Burgdorf, Jeffrey S., Moskal, Joseph R., Meltzer, Herbert Y.
Publicado no Behav Brain Res (2015)

Dual PI3K/mTOR inhibitors induce rapid over-activation of the MEK/ERK pathway in human pancreatic cancer cells through suppression of mTORC2

Por Soares, Heloisa P., Ming, Ming, Mellon, Michelle, Young, Steven H., Han, Liang, Sinnet-Smith, James, Rozengurt, Enrique
Publicado no Mol Cancer Ther (2015)

Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606

Por Wagner, Steven L., Rynearson, Kevin D., Duddy, Steven K., Zhang, Can, Nguyen, Phuong D., Becker, Ann, Vo, Uyen, Masliah, Deborah, Monte, Louise, Klee, Justin B., Echmalian, Corinne M., Xia, Weiming, Quinti, Luisa, Johnson, Graham, Lin, Jiunn H., Kim, Doo Y., Mobley, William C., Rissman, Robert A., Tanzi, Rudolph E.
Publicado no J Pharmacol Exp Ther (2017)

Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer

Por Overley-Adamson, Beth, Artlett, Carol M, Stephens, Connie, Sassi-Gaha, Sihem, Weis, Ransome D, Thacker, James D
Publicado em 2014

Quercetin Sensitizes Fluconazole-Resistant Candida albicans To Induce Apoptotic Cell Death by Modulating Quorum Sensing

Por Singh, B. N., Upreti, D. K., Singh, B. R., Pandey, G., Verma, S., Roy, S., Naqvi, A. H., Rawat, A. K. S.
Publicado no Antimicrob Agents Chemother (2015)

Xyloketal B Attenuates Atherosclerotic Plaque Formation and Endothelial Dysfunction in Apolipoprotein E Deficient Mice

Por Zhao, Li-Yan, Li, Jie, Yuan, Feng, Li, Mei, Zhang, Quan, Huang, Yun-Ying, Pang, Ji-Yan, Zhang, Bin, Sun, Fang-Yun, Sun, Hong-Shuo, Li, Qian, Cao, Lu, Xie, Yu, Lin, Yong-Cheng, Liu, Jie, Tan, Hong-Mei, Wang, Guan-Lei
Publicado no Mar Drugs (2015)

Role of chrysin on expression of insulin signaling molecules

Por Satyanarayana, Kottireddy, Sravanthi, Koora, Shaker, Ivvala Anand, Ponnulakshmi, Rajagopal, Selvaraj, Jayaraman
Publicado no J Ayurveda Integr Med (2015)