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Restoration of Rostral Ventrolateral Medulla Cystathionine-γ Lyase Activity Underlies Moxonidine-Evoked Neuroprotection and Sympathoinhibition in Diabetic Rats
We recently demonstrated a fundamental role for cystathionine-γ lyase (CSE)–derived hydrogen sulfide (H(2)S) in the cardioprotective effect of the centrally acting drug moxonidine in diabetic rats. Whether a downregulated CSE/H(2)S system in the rostral ventrolateral medulla (RVLM) underlies neurona...
Enregistré dans:
| Publié dans: | J Pharmacol Exp Ther |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771313/ https://ncbi.nlm.nih.gov/pubmed/29133386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.243865 |
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