Cystathionine-γ lyase-derived hydrogen sulfide mediates the cardiovascular protective effects of moxonidine in diabetic rats

Blunted cystathionine-γ lyase (CSE) activity (reduced endogenous H(2)S-level) is implicated in hypertension and myocardial dysfunction in diabetes. Here, we tested the hypothesis that CSE derived H(2)S mediates the cardiovascular protection conferred by the imidazoline I(1) receptor agonist moxonidi...

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Pubblicato in:Eur J Pharmacol
Autori principali: El-Sayed, Shaimaa S., Zakaria, Mohamed NM., Abdel-Ghany, Rasha H., Abdel-Rahman, Abdel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893977/
https://ncbi.nlm.nih.gov/pubmed/27138707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.04.054
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