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GLYX-13 (rapastinel) ameliorates subchronic phencyclidine- and ketamine-induced declarative memory deficits in mice

GLYX-13 (rapastinel), a tetrapeptide (Thr-Pro-Pro-Thr-amide), has been reported to have fast acting antidepressant properties in man based upon its N-methyl-d-aspartate receptor (NMDAR) glycine site functional partial agonism. Ketamine, a non-competitive NMDAR antagonist, also reported to have fast...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Rajagopal, Lakshmi, Burgdorf, Jeffrey S., Moskal, Joseph R., Meltzer, Herbert Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721234/
https://ncbi.nlm.nih.gov/pubmed/26632337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2015.10.060
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