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TPA-023 attenuates subchronic phencyclidine-induced declarative and reversal learning deficits via GABA(A) receptor agonist mechanism: possible therapeutic target for cognitive deficit in schizophrenia

GABAergic drugs are of interest for the treatment of anxiety, depression, bipolar disorder, pain, cognitive impairment associated with schizophrenia (CIAS), and other neuropsychiatric disorders. Some evidence suggests that TPA-023, (7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2...

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Detaylı Bibliyografya
Yayımlandı:Neuropsychopharmacology
Asıl Yazarlar: Rajagopal, Lakshmi, Huang, Mei, Michael, Eric, Kwon, Sunoh, Meltzer, Herbert Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6180114/
https://ncbi.nlm.nih.gov/pubmed/30093697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0160-3
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