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Subchronic phencyclidine treatment in adult mice increases GABAergic transmission and LTP threshold in the hippocampus

Repeated administration of non-competitive N-methyl-d-aspartate (NMDA) receptor antagonists such as phencyclidine (PCP) to rodents causes long-lasting deficits in cognition and memory, and has effects on behaviors that have been suggested to be models of the cognitive impairment associated with schi...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Nomura, Toshihiro, Oyamada, Yoshihiro, Fernandes, Herman B., Remmers, Christine, Xu, Jian, Meltzer, Herbert, Contractor, Anis
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584174/
https://ncbi.nlm.nih.gov/pubmed/25937215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.04.012
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