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Epac2 Mediates cAMP-Dependent Potentiation of Neurotransmission in the Hippocampus

Presynaptic terminal cAMP elevation plays a central role in plasticity at the mossy fiber-CA3 synapse of the hippocampus. Prior studies have identified protein kinase A as a downstream effector of cAMP that contributes to mossy fiber LTP (MF-LTP), but the potential contribution of Epac2, another cAM...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Fernandes, Herman B., Riordan, Sean, Nomura, Toshihiro, Remmers, Christine L., Kraniotis, Stephen, Marshall, John J., Kukreja, Lokesh, Vassar, Robert, Contractor, Anis
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405561/
https://ncbi.nlm.nih.gov/pubmed/25904804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0314-14.2015
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